{"id":126777,"date":"2021-08-27T09:22:59","date_gmt":"2021-08-27T16:22:59","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/08\/visual-response-shows-promise-as-biomarker-in-autism-linked-condition"},"modified":"2021-08-27T09:22:59","modified_gmt":"2021-08-27T16:22:59","slug":"visual-response-shows-promise-as-biomarker-in-autism-linked-condition","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/08\/visual-response-shows-promise-as-biomarker-in-autism-linked-condition","title":{"rendered":"Visual response shows promise as biomarker in autism-linked condition"},"content":{"rendered":"

<\/a><\/p>\n

Because the brain responses in children with different forms of autism overlapped, future therapies that are effective for Phelan-McDermid syndrome could potentially help other autistic children with similar neural patterns, Siper says.<\/p>\n

\n

Brain responses to visual stimuli are smaller and weaker in children with Phelan-McDermid syndrome<\/a>, an autism-linked genetic condition, than in non-autistic children, according to a new study. The difference in response is greater in children with larger genetic mutations.<\/p>\n

Mutations or deletions in SHANK3<\/a>, one of the genes most strongly linked to autism, cause Phelan-McDermid syndrome. More than 80 percent of people with the condition have autism; they also often have intellectual disability, developmental delays and other medical issues, though these traits and their severity can vary widely.<\/p>\n

The new study is the first to use electroencephalography (EEG) to measure visual evoked potentials \u2014 brain responses that occur shortly after a person views a visual stimulus \u2014 in people with Phelan-McDermid syndrome. The team previously identified differences<\/a> in these responses in people with \u2018idiopathic\u2019 autism, or autism with no known genetic cause. Other researchers have linked atypical visual evoked potentials to other single-gene causes of autism, such as Rett syndrome<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Because the brain responses in children with different forms of autism overlapped, future therapies that are effective for Phelan-McDermid syndrome could potentially help other autistic children with similar neural patterns, Siper says. Brain responses to visual stimuli are smaller and weaker in children with Phelan-McDermid syndrome, an autism-linked genetic condition, than in non-autistic children, according [\u2026]<\/p>\n","protected":false},"author":621,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-126777","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/126777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/621"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=126777"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/126777\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=126777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=126777"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=126777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}