{"id":126217,"date":"2021-08-14T07:23:10","date_gmt":"2021-08-14T14:23:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/08\/how-a-specific-synapse-type-regulates-anxiety-like-behavior"},"modified":"2021-08-14T07:23:10","modified_gmt":"2021-08-14T14:23:10","slug":"how-a-specific-synapse-type-regulates-anxiety-like-behavior","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/08\/how-a-specific-synapse-type-regulates-anxiety-like-behavior","title":{"rendered":"How a Specific Synapse Type Regulates Anxiety-Like Behavior"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-a-specific-synapse-type-regulates-anxiety-like-behavior.jpg\"><\/a><\/p>\n<p>\u201cOur research may help us understand how abnormalities in anxiety-like behavior occur and design circuit-based therapeutic approaches for correcting them,\u201d remarks Professor Ji Won Um from the Department of Brain and Cognitive Sciences at DGIST, who led the study.<\/p>\n<hr>\n<p>\n<strong><em>Summary: <\/em><\/strong><em>Study identifies the role a specific protein plays in regulating the development of inhibitory synapses in the hippocampus in the context of anxiety-related behaviors.<\/em><\/p>\n<p><strong><em>Source: <\/em><\/strong><em>DGIST<\/em><\/p>\n<p><strong>The mechanisms behind the organization of neuronal synapses remain unclear owing to the sheer number of genes, proteins, and neuron types involved. In a recent study, Daegu Gyeongbuk Institute of Science and Technology scientists conducted a series of experiments in genetically modified mice to clarify the role of two proteins in regulating the development of inhibitory synapses in the hippocampus, in the context of anxiety-related behaviors, paving the way to better understand the brain.<\/strong><\/p>\n<p>The correct functioning of our brain, as well as that of other animals, depends on a very intricate interplay between multiple types of neurons. These interactions are orchestrated by multitudes of synaptic proteins; thus, pinpointing their specific functions is extremely challenging. In particular, the molecular mechanisms that regulate the plasticity of synapses are not completely understood.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cOur research may help us understand how abnormalities in anxiety-like behavior occur and design circuit-based therapeutic approaches for correcting them,\u201d remarks Professor Ji Won Um from the Department of Brain and Cognitive Sciences at DGIST, who led the study. Summary: Study identifies the role a specific protein plays in regulating the development of inhibitory synapses [\u2026]<\/p>\n","protected":false},"author":621,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,47],"tags":[],"class_list":["post-126217","post","type-post","status-publish","format-standard","hentry","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/126217","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/621"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=126217"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/126217\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=126217"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=126217"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=126217"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}