{"id":125941,"date":"2021-08-06T17:22:47","date_gmt":"2021-08-07T00:22:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/08\/how-mutations-in-top-autism-gene-could-lead-to-seizures"},"modified":"2021-08-06T17:22:47","modified_gmt":"2021-08-07T00:22:47","slug":"how-mutations-in-top-autism-gene-could-lead-to-seizures","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/08\/how-mutations-in-top-autism-gene-could-lead-to-seizures","title":{"rendered":"How mutations in top autism gene could lead to seizures"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-mutations-in-top-autism-gene-could-lead-to-seizures.jpg\"><\/a><\/p>\n<p>Some mutations that disable SCN2A, one of the genes most strongly linked to autism, can unexpectedly make neurons hyperexcitable, a study in mice shows. The findings may help explain why a sizeable proportion of autistic children with mutations in SCN2A experience epileptic seizures.<\/p>\n<hr>\n<p>Deleterious mutations in an autism-associated gene can make neurons hyperexcitable, raising the risk of epileptic seizures.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Some mutations that disable SCN2A, one of the genes most strongly linked to autism, can unexpectedly make neurons hyperexcitable, a study in mice shows. The findings may help explain why a sizeable proportion of autistic children with mutations in SCN2A experience epileptic seizures. Deleterious mutations in an autism-associated gene can make neurons hyperexcitable, raising the [\u2026]<\/p>\n","protected":false},"author":621,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,47],"tags":[],"class_list":["post-125941","post","type-post","status-publish","format-standard","hentry","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/125941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/621"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=125941"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/125941\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=125941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=125941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=125941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}