{"id":125189,"date":"2021-07-20T11:26:23","date_gmt":"2021-07-20T18:26:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/07\/new-protein-folding-ai-just-made-a-once-in-a-generation-advance-in-biology"},"modified":"2021-07-20T11:26:23","modified_gmt":"2021-07-20T18:26:23","slug":"new-protein-folding-ai-just-made-a-once-in-a-generation-advance-in-biology","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/07\/new-protein-folding-ai-just-made-a-once-in-a-generation-advance-in-biology","title":{"rendered":"New Protein Folding AI Just Made a \u2018Once In a Generation\u2019 Advance in Biology"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-protein-folding-ai-just-made-a-once-in-a-generation-advance-in-biology2.jpg\"><\/a><\/p>\n<p>The tool next examines how one protein\u2019s amino acids interact with another within the same protein, for example, by examining the distance between two distant building blocks. It\u2019s like looking at your hands and feet fully stretched out, versus in a backbend measuring the distance between those extremities as you \u201cfold\u201d into a yoga pose.<\/p>\n<p>Finally, the third track looks at 3D coordinates of each atom that makes up a protein building block\u2014kind of like mapping the studs on a Lego block\u2014to compile the final 3D structure. The network then bounces back and forth between these tracks, so that one output can update another track.<\/p>\n<p>The end results came close to those of DeepMind\u2019s tool, AlphaFold2, which matched the gold standard of structures obtained from experiments. Although RoseTTAFold wasn\u2019t as accurate as AlphaFold2, it seemingly required much less time and energy. For a simple protein, the algorithm was able to solve the structure using a gaming computer in about 10 minutes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The tool next examines how one protein\u2019s amino acids interact with another within the same protein, for example, by examining the distance between two distant building blocks. It\u2019s like looking at your hands and feet fully stretched out, versus in a backbend measuring the distance between those extremities as you \u201cfold\u201d into a yoga pose. [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,41,1965,48,6],"tags":[],"class_list":["post-125189","post","type-post","status-publish","format-standard","hentry","category-biological","category-information-science","category-mapping","category-particle-physics","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/125189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=125189"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/125189\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=125189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=125189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=125189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}