{"id":124738,"date":"2021-07-09T12:22:37","date_gmt":"2021-07-09T19:22:37","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/07\/off-patent-osteoporosis-drug-also-found-to-extend-lifespan"},"modified":"2021-07-09T12:22:37","modified_gmt":"2021-07-09T19:22:37","slug":"off-patent-osteoporosis-drug-also-found-to-extend-lifespan","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/07\/off-patent-osteoporosis-drug-also-found-to-extend-lifespan","title":{"rendered":"Off-Patent Osteoporosis Drug Also Found to Extend Lifespan"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/off-patent-osteoporosis-drug-also-found-to-extend-lifespan2.jpg\"><\/a><\/p>\n<p><a href=\"https:\/\/www.lifespan.io\/news\/life-extension-drug-discovered-by-accident\/\">Zoledronate is a biophosphonate, a drug used to strengthen bones and reduce the risk of osteoporosis-related bone fractures.<\/a> It is well-absorbed into the bones, so it only needs to be administered through infusion once a year.<\/p>\n<p>A 2010 study had found that people who were given zoledronate after experiencing hip fractures showed slightly reduced all-cause mortality compared to a control group. Patients who took the drug were at significantly lower risk for heart arrhythmias and pneumonia.<\/p>\n<p>As this is a drug that is already being given to people, the choice to go back to genetically modified fruit flies, a much simpler model of aging, may seem counterintuitive. The team chose to test these insects for two principal reasons. The first is that Drosophila flies are a common subject of studies on basic aging pathways, which the researchers wished to explore. The second is simpler: Drosophila flies lack bones, making the bone-affecting properties of zoledronate irrelevant to the study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Zoledronate is a biophosphonate, a drug used to strengthen bones and reduce the risk of osteoporosis-related bone fractures. It is well-absorbed into the bones, so it only needs to be administered through infusion once a year. A 2010 study had found that people who were given zoledronate after experiencing hip fractures showed slightly reduced all-cause [\u2026]<\/p>\n","protected":false},"author":426,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269],"tags":[],"class_list":["post-124738","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/124738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/426"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=124738"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/124738\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=124738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=124738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=124738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}