{"id":124377,"date":"2021-06-28T15:22:20","date_gmt":"2021-06-28T22:22:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/06\/first-crispr-based-gene-drive-developed-in-plants"},"modified":"2021-06-28T15:22:20","modified_gmt":"2021-06-28T22:22:20","slug":"first-crispr-based-gene-drive-developed-in-plants","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/06\/first-crispr-based-gene-drive-developed-in-plants","title":{"rendered":"First CRISPR-Based Gene Drive Developed in Plants"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/first-crispr-based-gene-drive-developed-in-plants3.jpg\"><\/a><\/p>\n<p>For the first time, CRISPR-Cas9-based gene drive technology has been developed in plants. Enabling the inheritance of both copies of a target gene from a single parent could greatly reduce the generations needed for plant breeding. Establishing this genome editing technology in plants may allow for breeding resilient crops that are better able to withstand drought and disease.<\/p>\n<p>#GenomeEditing #AgBio #CRISPR #Cas9<\/p>\n<hr>\n<p>Gene drives have been established in insects, including fruit flies and mosquitoes, and mammals such as mice. Now, for the first time, the CRISPR-Cas9-based technology that disrupts Mendelian inheritance and allows for selective acquisition of target genes has been developed in plants. Establishing this genome editing technology in plants may allow for breeding resilient crops that are better able to withstand drought and disease.<\/p>\n<p>The research is published in <em>Nature Communications<\/em> in the paper, \u201c<a href=\"https:\/\/www.nature.com\/articles\/s41467-021-24195-5\" target=\"_blank\" rel=\"noopener\">Selective inheritance of target genes from only one parent of sexually reproduced F1 progeny in <em>Arabidopsis<\/em><\/a>.\u201d<\/p>\n<p>\u201cThis work defies the genetic constraints of sexual reproduction that an offspring inherits 50% of their genetic materials from each parent,\u201d said Yunde Zhao, PhD, professor of cell and developmental biology at the University of California, San Diego (UCSD). \u201cThis work enables inheritance of both copies of the desired genes from only a single parent. The findings can greatly reduce the generations needed for plant breeding.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For the first time, CRISPR-Cas9-based gene drive technology has been developed in plants. Enabling the inheritance of both copies of a target gene from a single parent could greatly reduce the generations needed for plant breeding. Establishing this genome editing technology in plants may allow for breeding resilient crops that are better able to withstand [\u2026]<\/p>\n","protected":false},"author":621,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1506,412],"tags":[],"class_list":["post-124377","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-food","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/124377","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/621"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=124377"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/124377\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=124377"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=124377"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=124377"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}