{"id":12437,"date":"2014-10-02T09:00:40","date_gmt":"2014-10-02T16:00:40","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/?p=12437"},"modified":"2017-04-25T04:12:04","modified_gmt":"2017-04-25T11:12:04","slug":"synthetic-molecule-uses-salt-to-trigger-self-destruction-of-cancer-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2014\/10\/synthetic-molecule-uses-salt-to-trigger-self-destruction-of-cancer-cells","title":{"rendered":"Synthetic molecule uses salt to trigger self-destruction of cancer cells"},"content":{"rendered":"<p>By <a href=\"http:\/\/www.gizmag.com\/author\/nick-lavars\/\" rel=\"author\">Nick Lavars<\/a> \u2014 GizMag<\/p>\n<p><\/p>\n<p>A team of international researchers has developed a molecule capable of triggering cancer cell death by carrying chloride into cancer cell membranes. The molecule flushes the cells with salt and causes them to self-destruct, potentially paving the way for new types of anti-cancer drugs.<\/p>\n<p>The international effort involves researchers from the UK, Texas and South Korea who have collaborated to develop a synthetic ion transporter with a chloride payload. Once it reaches the cancer cells, the chloride interacts with the sodium in the cell membranes and leads to its demise.<\/p>\n<p>\u201cThis work shows how chloride transporters can work with sodium channels in cell membranes to cause an influx of salt into a cell,\u201d says the University of Southampton\u2019s Professor Phillip Gale, one of the study\u2019s co-authors. \u201cWe found we can trigger cell death with salt.\u201d<\/p>\n<p><a href=\"http:\/\/www.gizmag.com\/molecule-self-destruction-cancer-cell-salt\/33331\/\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>By Nick Lavars \u2014 GizMag A team of international researchers has developed a molecule capable of triggering cancer cell death by carrying chloride into cancer cell membranes. The molecule flushes the cells with salt and causes them to self-destruct, potentially paving the way for new types of anti-cancer drugs. The international effort involves researchers from [\u2026]<\/p>\n","protected":false},"author":76,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-12437","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/12437","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/76"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=12437"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/12437\/revisions"}],"predecessor-version":[{"id":46848,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/12437\/revisions\/46848"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=12437"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=12437"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=12437"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}