{"id":124332,"date":"2021-06-27T00:22:18","date_gmt":"2021-06-27T07:22:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/06\/500-lifespan-increase-achieved-in-nematode-worms"},"modified":"2021-06-27T00:22:18","modified_gmt":"2021-06-27T07:22:18","slug":"500-lifespan-increase-achieved-in-nematode-worms","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/06\/500-lifespan-increase-achieved-in-nematode-worms","title":{"rendered":"500% Lifespan Increase Achieved in Nematode Worms"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/500-lifespan-increase-achieved-in-nematode-worms.jpg\"><\/a><\/p>\n<p>Caenorhabditis elegans is a nematode worm which is commonly utilised in longevity research due to their genetic similarity to humans and their extremely short lifespans (often no more than 4 weeks). Previous research into improving the lifespan of these worms has yielded several interesting results, with modifications to their insulin and rapamycin signalling pathways resulting in a 100% and 30% increase in lifespan respectively. These successes prompted the obvious question, what would happen if both of these pathways were modified at the same time?<\/p>\n<p>Photograph of the Caenorhabditis elegans adult hermaphrodite. Scale bar, 100 \u03bcm. Credit: ResearchGate, Nobuyuki Hamada.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Caenorhabditis elegans is a nematode worm which is commonly utilised in longevity research due to their genetic similarity to humans and their extremely short lifespans (often no more than 4 weeks). Previous research into improving the lifespan of these worms has yielded several interesting results, with modifications to their insulin and rapamycin signalling pathways resulting [\u2026]<\/p>\n","protected":false},"author":626,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[412,269],"tags":[],"class_list":["post-124332","post","type-post","status-publish","format-standard","hentry","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/124332","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/626"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=124332"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/124332\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=124332"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=124332"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=124332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}