{"id":122915,"date":"2021-05-22T19:22:18","date_gmt":"2021-05-23T02:22:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/05\/imiquimod-spurs-regression-of-high-grade-cervical-lesions"},"modified":"2021-05-22T19:22:18","modified_gmt":"2021-05-23T02:22:18","slug":"imiquimod-spurs-regression-of-high-grade-cervical-lesions","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/05\/imiquimod-spurs-regression-of-high-grade-cervical-lesions","title":{"rendered":"Imiquimod Spurs Regression of High-Grade Cervical Lesions"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/imiquimod-spurs-regression-of-high-grade-cervical-lesions2.jpg\"><\/a><\/p>\n<p>Einstein, who was not involved in the study, noted that the number of LEEP procedures performed per year in the U.S. \u2014 approximately 500000 \u2014 indicates the scope of the disease. Additionally, he pointed out that due to the association between LEEP and preterm births, \u201cit is truly important to explore these nonsurgical agents.\u201d<\/p>\n<p>Imiquimod directly activates innate immune cells through Toll-like receptors 7 and 8, resulting in production of cytokines and interferons.<\/p>\n<p>Fonseca and colleagues evaluated the histologic response of cervical HSIL \u2014 defined as regression to cervical intraepithelial neoplasia (CIN) 1 \u2014 after topical application of 5% imiquimod cream.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Einstein, who was not involved in the study, noted that the number of LEEP procedures performed per year in the U.S. \u2014 approximately 500000 \u2014 indicates the scope of the disease. Additionally, he pointed out that due to the association between LEEP and preterm births, \u201cit is truly important to explore these nonsurgical agents.\u201d Imiquimod [\u2026]<\/p>\n","protected":false},"author":621,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-122915","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/122915","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/621"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=122915"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/122915\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=122915"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=122915"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=122915"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}