{"id":121449,"date":"2021-04-11T19:22:58","date_gmt":"2021-04-12T02:22:58","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/04\/penn-scientists-correct-genetic-blindness-with-a-single-injection-into-the-eye"},"modified":"2021-04-11T19:22:58","modified_gmt":"2021-04-12T02:22:58","slug":"penn-scientists-correct-genetic-blindness-with-a-single-injection-into-the-eye","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/04\/penn-scientists-correct-genetic-blindness-with-a-single-injection-into-the-eye","title":{"rendered":"Penn Scientists Correct Genetic Blindness With a Single Injection into the Eye"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/penn-scientists-correct-genetic-blindness-with-a-single-injection-into-the-eye2.jpg\"><\/a><\/p>\n<p>Antisense oligonucleotide therapy works by altering the RNA, the messenger that carries instructions from your DNA to crank out proteins.<\/p>\n<p>An article in <a href=https:\/\/www.nature.com\/articles\/nrneurol.2017.148 rel=\"nofollow noopener\" target=_blank>Nature Reviews Neurology<\/a> describes antisense oligonucleotides as \u201cshort, synthetic, single-strand\u201d molecules, which can alter RNA to cause protein creation to be reduced, enhanced, or modified.<\/p>\n<p>In the Penn study, the targeted protein was created by the mutated LCA gene.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antisense oligonucleotide therapy works by altering the RNA, the messenger that carries instructions from your DNA to crank out proteins. An article in Nature Reviews Neurology describes antisense oligonucleotides as \u201cshort, synthetic, single-strand\u201d molecules, which can alter RNA to cause protein creation to be reduced, enhanced, or modified. In the Penn study, the targeted protein [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-121449","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/121449","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=121449"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/121449\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=121449"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=121449"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=121449"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}