{"id":120749,"date":"2021-03-21T04:23:57","date_gmt":"2021-03-21T11:23:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/03\/hdl-update-age-related-changes-all-cause-mortality-risk-and-progress-towards-the-optimal-range"},"modified":"2021-03-21T04:23:57","modified_gmt":"2021-03-21T11:23:57","slug":"hdl-update-age-related-changes-all-cause-mortality-risk-and-progress-towards-the-optimal-range","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/03\/hdl-update-age-related-changes-all-cause-mortality-risk-and-progress-towards-the-optimal-range","title":{"rendered":"HDL Update: Age-Related Changes, All-Cause Mortality Risk, And Progress Towards The Optimal Range"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/MUuKlpyvZaU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Here\u2019s my latest video!<\/p>\n<hr>\n<p>In November 2020, I made a HDL video based on a meta-analysis in ~3.4 million subjects that was published in July 2020. In Dec 2020, a larger study (n=15.8 million subjects) was published-those data are presented in the video, and compared against the meta-analysis.<\/p>\n<p>In addition, I\u2019ve tested my HDL 2 more times since November 2020, so how\u2019s my progress for getting it into the optimal range? Also, I attempt to derive clinical significance by identifying correlations for higher HDL with lower Lp(a) and hs-CRP.<\/p>\n<p>Studies referenced in the video:<br \/> High-density lipoprotein cholesterol and all-cause mortality by sex and age: a prospective cohort study among 15.8 million adults:<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33313654\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33313654\/<\/a><\/p>\n<p>HDL-C is associated with mortality from all causes, cardiovascular disease and cancer in a J-shaped dose-response fashion: a pooled analysis of 37 prospective cohort studies:<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2021\/03\/hdl-update-age-related-changes-all-cause-mortality-risk-and-progress-towards-the-optimal-range\">Continue reading \u201cHDL Update: Age-Related Changes, All-Cause Mortality Risk, And Progress Towards The Optimal Range\u201d | &gt;<\/a><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Here\u2019s my latest video! In November 2020, I made a HDL video based on a meta-analysis in ~3.4 million subjects that was published in July 2020. In Dec 2020, a larger study (n=15.8 million subjects) was published-those data are presented in the video, and compared against the meta-analysis. In addition, I\u2019ve tested my HDL 2 [\u2026]<\/p>\n","protected":false},"author":587,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,1901],"tags":[],"class_list":["post-120749","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-sex"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/120749","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/587"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=120749"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/120749\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=120749"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=120749"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=120749"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}