{"id":119783,"date":"2021-02-20T00:22:25","date_gmt":"2021-02-20T08:22:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/02\/in-situ-measurements-of-intracellular-thermal-conductivity-using-heater-thermometer-hybrid-diamond-nanosensors"},"modified":"2021-02-20T00:22:25","modified_gmt":"2021-02-20T08:22:25","slug":"in-situ-measurements-of-intracellular-thermal-conductivity-using-heater-thermometer-hybrid-diamond-nanosensors","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/02\/in-situ-measurements-of-intracellular-thermal-conductivity-using-heater-thermometer-hybrid-diamond-nanosensors","title":{"rendered":"In situ measurements of intracellular thermal conductivity using heater-thermometer hybrid diamond nanosensors"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/in-situ-measurements-of-intracellular-thermal-conductivity-using-heater-thermometer-hybrid-diamond-nanosensors3.jpg\"><\/a><\/p>\n<p>Understanding heat dissipation processes at nanoscale during cellular thermogenesis is essential to clarify the relationships between the heat and biological processes in cells and organisms. A key parameter determining the heat flux inside a cell is the local thermal conductivity, a factor poorly investigated both experimentally and theoretically. Here, using a nanoheater\/nanothermometer hybrid made of a polydopamine encapsulating a fluorescent nanodiamond, we measured the intracellular thermal conductivities of HeLa and MCF-7 cells with a spatial resolution of about 200 nm. The mean values determined in these two cell lines are both 0.11 \u00b1 0.04 W m\u22121 K\u22121, which is significantly smaller than that of water. Bayesian analysis of the data suggests there is a variation of the thermal conductivity within a cell.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Understanding heat dissipation processes at nanoscale during cellular thermogenesis is essential to clarify the relationships between the heat and biological processes in cells and organisms. A key parameter determining the heat flux inside a cell is the local thermal conductivity, a factor poorly investigated both experimentally and theoretically. Here, using a nanoheater\/nanothermometer hybrid made of [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,4],"tags":[],"class_list":["post-119783","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/119783","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=119783"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/119783\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=119783"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=119783"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=119783"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}