{"id":119446,"date":"2021-02-11T10:34:57","date_gmt":"2021-02-11T18:34:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2021\/02\/mechanochemical-bond-scission-for-the-activation-of-drugs"},"modified":"2021-02-11T10:34:57","modified_gmt":"2021-02-11T18:34:57","slug":"mechanochemical-bond-scission-for-the-activation-of-drugs","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2021\/02\/mechanochemical-bond-scission-for-the-activation-of-drugs","title":{"rendered":"Mechanochemical bond scission for the activation of drugs"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mechanochemical-bond-scission-for-the-activation-of-drugs.jpg\"><\/a><\/p>\n<p>Stimuli-responsive control of drug activation can mitigate issues caused by poor drug selectivity. Now, it has been shown that mechanical force\u2014induced by ultrasound\u2014can be used to activate drugs in three different systems. This approach has enabled the activation of antibiotics or a cytotoxic anticancer agent from synthetic polymers, polyaptamers and nanoparticle assemblies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Stimuli-responsive control of drug activation can mitigate issues caused by poor drug selectivity. Now, it has been shown that mechanical force\u2014induced by ultrasound\u2014can be used to activate drugs in three different systems. This approach has enabled the activation of antibiotics or a cytotoxic anticancer agent from synthetic polymers, polyaptamers and nanoparticle assemblies.<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,4],"tags":[],"class_list":["post-119446","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/119446","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=119446"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/119446\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=119446"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=119446"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=119446"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}