{"id":117458,"date":"2020-12-20T14:22:45","date_gmt":"2020-12-20T22:22:45","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/12\/epigenetic-aging-how-old-is-your-dna"},"modified":"2020-12-20T14:22:45","modified_gmt":"2020-12-20T22:22:45","slug":"epigenetic-aging-how-old-is-your-dna","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/12\/epigenetic-aging-how-old-is-your-dna","title":{"rendered":"Epigenetic Aging: How old is your DNA?"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/_il_U7lH8wc?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging \u2013 a type of \u201cclock\u201d \u2013 based on the methylation pattern of an organism\u2019s genome. Methylations are biochemical processes that modify the activity of a DNA segment without changing its sequence \u2013 a type of epigenetic change. This video primer explains the basics of epigenetic clocks, the topic of our interview with Dr. Steve Horvath, coming soon!<\/p>\n<p>Get the show notes here:<br \/>\n<a href=\"https:\/\/www.foundmyfitness.com\/episodes\/epigenetic-clock\/\">https:\/\/www.foundmyfitness.com\/episodes\/epigenetic-clock\/<\/a><\/p>\n<p>Episode highlights:<br \/> \u2022 00:00:09 \u2014 A person\u2019s risk of disease is more dependent on their biological age than their chronological age.<br \/> \u2022 00:00:09 \u2014 Epigenetics refers to processes that can affect gene expression without changing the DNA sequence. Methylation is a type of epigenetic change that occurs over a lifetime in a predictable way and can be used to measure biological age.<br \/> \u2022 00:01:17 \u2014 The Horvath clock can accurately predict a person\u2019s chronological age based on only the epigenetic information in their blood.<br \/> \u2022 00:01:54 \u2014 The GrimAge clock can predict the risk and time of onset of cancer, heart disease, and death.<br \/> \u2022 00:02:19 \u2014 Certain drugs can reverse a person\u2019s epigenetic age, but the effects on biological age are unknown.<br \/> \u2022 00:03:09 \u2014 The discovery of an anti-aging drug is on the horizon.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Steve Horvath, a professor of genetics and biostatistics at UCLA, has found a way to measure biological aging \u2013 a type of \u201cclock\u201d \u2013 based on the methylation pattern of an organism\u2019s genome. Methylations are biochemical processes that modify the activity of a DNA segment without changing its sequence \u2013 a type of epigenetic [\u2026]<\/p>\n","protected":false},"author":530,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,412,269],"tags":[],"class_list":["post-117458","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-genetics","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/117458","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/530"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=117458"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/117458\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=117458"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=117458"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=117458"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}