{"id":112555,"date":"2020-09-05T09:24:07","date_gmt":"2020-09-05T16:24:07","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/09\/using-crispr-to-improve-viral-vectors-for-gene-therapy"},"modified":"2020-09-05T09:24:07","modified_gmt":"2020-09-05T16:24:07","slug":"using-crispr-to-improve-viral-vectors-for-gene-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/09\/using-crispr-to-improve-viral-vectors-for-gene-therapy","title":{"rendered":"Using CRISPR to improve viral vectors for gene therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/using-crispr-to-improve-viral-vectors-for-gene-therapy.jpg\"><\/a><\/p>\n<p>To overcome preexisting immunity that cripples the adenovirus vectors used in gene therapy and vaccines, scientists at the University of Pittsburgh created a CRISPR-based system that briefly suppresses the genes that cause the problem. The method improved gene therapy uptake in mice and is being developed by startup SafeGen.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>To overcome preexisting immunity that cripples the adenovirus vectors used in gene therapy and vaccines, scientists at the University of Pittsburgh created a CRISPR-based system that briefly suppresses the genes that cause the problem. The method improved gene therapy uptake in mice and is being developed by startup SafeGen.<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-112555","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/112555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=112555"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/112555\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=112555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=112555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=112555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}