{"id":111979,"date":"2020-08-27T12:22:54","date_gmt":"2020-08-27T19:22:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/08\/blocking-nerve-signals-to-the-pancreas-halts-type-1-diabetes-onset-in-mice"},"modified":"2020-08-27T12:22:54","modified_gmt":"2020-08-27T19:22:54","slug":"blocking-nerve-signals-to-the-pancreas-halts-type-1-diabetes-onset-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/08\/blocking-nerve-signals-to-the-pancreas-halts-type-1-diabetes-onset-in-mice","title":{"rendered":"Blocking nerve signals to the pancreas halts type 1 diabetes onset in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/blocking-nerve-signals-to-the-pancreas-halts-type-1-diabetes-onset-in-mice.jpg\"><\/a><\/p>\n<p>Your pancreas is a little sweet potato-shaped organ that sits snug behind your stomach. The pancreas is studded with islets, the cell clusters that house insulin-producing beta cells. In people with type 1 diabetes, the body\u2019s own immune cells head for the islets and start attacking the beta cells. No one knows exactly what triggers this attack.<\/p>\n<p>One clue may lie in the pattern of beta cell death. Many beta <a href=\"https:\/\/medicalxpress.com\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a> are killed off in big patches while other beta cells are mysteriously untouched. Something seems to be drawing <a href=\"https:\/\/medicalxpress.com\/tags\/immune+cells\/\" rel=\"tag\" class=\"\">immune cells<\/a> to attack specific groups of <a href=\"https:\/\/medicalxpress.com\/tags\/beta+cells\/\" rel=\"tag\" class=\"\">beta cells<\/a> while ignoring others.<\/p>\n<p>In a new <i>Science Advances<\/i> study, researchers at La Jolla Institute for Immunology (LJI) report that the nervous system may be driving this patchy cell die-off. Their new findings in a mouse model suggest that blocking nerve signals to the pancreas could stop patients from ever developing type 1 diabetes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Your pancreas is a little sweet potato-shaped organ that sits snug behind your stomach. The pancreas is studded with islets, the cell clusters that house insulin-producing beta cells. In people with type 1 diabetes, the body\u2019s own immune cells head for the islets and start attacking the beta cells. No one knows exactly what triggers [\u2026]<\/p>\n","protected":false},"author":426,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-111979","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/111979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/426"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=111979"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/111979\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=111979"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=111979"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=111979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}