{"id":110646,"date":"2020-07-30T13:42:20","date_gmt":"2020-07-30T20:42:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/07\/trial-data-support-dexamethasone-but-not-hydroxychloroquine-for-covid-19"},"modified":"2020-07-30T13:42:20","modified_gmt":"2020-07-30T20:42:20","slug":"trial-data-support-dexamethasone-but-not-hydroxychloroquine-for-covid-19","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/07\/trial-data-support-dexamethasone-but-not-hydroxychloroquine-for-covid-19","title":{"rendered":"Trial data support dexamethasone, but not hydroxychloroquine, for COVID-19"},"content":{"rendered":"<p><a class=\"blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/trial-data-support-dexamethasone-but-not-hydroxychloroquine-for-covid-19.jpg\"><\/a><\/p>\n<p>According to the University of Minnesota trial data supports dexamethasone over Hydroxychloroquine:<\/p>\n<hr>\n<p>Data from a large randomized controlled trial in the United Kingdom showing a benefit from use of the steroid dexamethasone in hospitalized COVID-19 patients was <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2021436\">released today<\/a> in the <em>New England Journal of Medicine<\/em> (<em>NEJM<\/em>), while two more studies show no benefit for the malaria drug hydroxychloroquine<em>.<\/em><\/p>\n<p>The <em>NEJM<\/em> data, which were originally reported in a press release in mid-June by the chief investigators of the RECOVERY (Randomized Evaluation of COVID-19 Therapy) trial after an interim analysis, show that in patients needing mechanical ventilation, dexamethasone reduced deaths by 36% compared with usual care. In patients receiving oxygen, the incidence of death was 18% lower for patients on dexamethasone.<\/p>\n<p>\u201cThe RECOVERY trial provides evidence that treatment with dexamethasone at a dose of 6 mg once daily for up to 10 days reduces 28-day mortality in patients with Covid-19 who are receiving respiratory support,\u201d investigators with the RECOVERY Collaborative Group, which is led by scientists from the University of Oxford, wrote.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>According to the University of Minnesota trial data supports dexamethasone over Hydroxychloroquine: Data from a large randomized controlled trial in the United Kingdom showing a benefit from use of the steroid dexamethasone in hospitalized COVID-19 patients was released today in the New England Journal of Medicine (NEJM), while two more studies show no benefit for [\u2026]<\/p>\n","protected":false},"author":461,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-110646","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/110646","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/461"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=110646"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/110646\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=110646"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=110646"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=110646"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}