{"id":110456,"date":"2020-07-25T08:10:10","date_gmt":"2020-07-25T15:10:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/07\/erk-mediated-mechanochemical-waves-direct-collective-cell-polarization"},"modified":"2020-07-25T08:10:10","modified_gmt":"2020-07-25T15:10:10","slug":"erk-mediated-mechanochemical-waves-direct-collective-cell-polarization","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/07\/erk-mediated-mechanochemical-waves-direct-collective-cell-polarization","title":{"rendered":"ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/erk-mediated-mechanochemical-waves-direct-collective-cell-polarization2.jpg\"><\/a><\/p>\n<p>During collective cell migration, directional information is transmitted from a leading edge to the follower cells as a form of ERK activation waves. Hino et al. demonstrate that a mechanochemical feedback loop coupling cell deformation and ERK activation enables sustained propagation of the directional information over a tissue-scale expanse.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>During collective cell migration, directional information is transmitted from a leading edge to the follower cells as a form of ERK activation waves. Hino et al. demonstrate that a mechanochemical feedback loop coupling cell deformation and ERK activation enables sustained propagation of the directional information over a tissue-scale expanse.<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"class_list":["post-110456","post","type-post","status-publish","format-standard","hentry","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/110456","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=110456"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/110456\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=110456"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=110456"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=110456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}