{"id":109600,"date":"2020-07-06T18:02:10","date_gmt":"2020-07-07T01:02:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/07\/translational-microbiomics-offsets-ecological-disruptions"},"modified":"2020-07-06T18:02:10","modified_gmt":"2020-07-07T01:02:10","slug":"translational-microbiomics-offsets-ecological-disruptions","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/07\/translational-microbiomics-offsets-ecological-disruptions","title":{"rendered":"Translational Microbiomics Offsets Ecological Disruptions"},"content":{"rendered":"

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Once an ecosystem is disturbed, restoring it can be difficult. And when the disturbed ecosystem is a patient\u2019s microbiome, restoring the patient to health can be even more difficult. Just one ecosystem element that proliferates or diminishes beyond bounds may throw multiple elements into disarray, creating a dysbiosis that resists simple remedies.<\/p>\n

Because a patient\u2019s microbiome consists of interacting elements\u2014including elements that extend beyond the microbiome itself\u2014these elements cannot be seen in isolation. Rather, they are dynamic parts of a systemic whole. Touch any one of them, and the effects of doing so may ripple outward in unpredictable ways\u2014unless the elements and their interactions are thoroughly understood.<\/p>\n

\u2026<\/p>\n

\u201cWe are covered by, and protected by, and interacted with by vast microbial ecosystems,\u201d says Julius Goepp, MD, founder of Scaled Microbiomics. Everywhere the body comes into contact with the outside environment, you\u2019ll find a thriving community of microbes. This includes places that are obviously \u201cexternal\u201d\u2014like skin and hair (including the skin and hair of underarms and nostrils)\u2014as well as places that we consider to be \u201cinternal,\u201d like the gastrointestinal tract.<\/p>\n

\u201cThe surface of our gut is continuous with the outside world,\u201d Goepp points out. The miracle of our gut, he continues, is that it can transport \u201ctwo pounds of very nasty material [while keeping] it one cell layer away from our precious, sterile, inside tissue.\u201d<\/p>\n

But one cell layer can prove precarious protection, especially if that microbial ecosystem gets out of balance. The gut\u2019s microbial ecosystem, Goepp suggests, is like the Amazon rainforest ecosystem in that it is resilient, but only to a point. When subjected to stressors such as prolonged exposure to antibiotics, a diet high in certain additives and low in fiber, and environmental pollution, the microbial ecosystem can be tipped far enough out of balance that a new normal becomes established. This is called dysbiosis, and it\u2019s increasingly linked with a number of noncommunicable diseases, such as diabetes, neurodegenerative diseases, and cancer.<\/p>\n

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Continue reading \u201cTranslational Microbiomics Offsets Ecological Disruptions\u201d | ><\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

Once an ecosystem is disturbed, restoring it can be difficult. And when the disturbed ecosystem is a patient\u2019s microbiome, restoring the patient to health can be even more difficult. Just one ecosystem element that proliferates or diminishes beyond bounds may throw multiple elements into disarray, creating a dysbiosis that resists simple remedies. Because a patient\u2019s [\u2026]<\/p>\n","protected":false},"author":501,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-109600","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/501"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=109600"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109600\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=109600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=109600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=109600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}