{"id":109599,"date":"2020-07-06T18:01:43","date_gmt":"2020-07-07T01:01:43","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/07\/compounds-halt-sars-cov-2-replication"},"modified":"2020-07-06T18:01:43","modified_gmt":"2020-07-07T01:01:43","slug":"compounds-halt-sars-cov-2-replication","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/07\/compounds-halt-sars-cov-2-replication","title":{"rendered":"Compounds halt SARS-CoV-2 replication"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/compounds-halt-sars-cov-2-replication3.jpg\"><\/a><\/p>\n<p>As the death toll from the COVID-19 pandemic mounts, scientists worldwide continue their push to develop effective treatments and a vaccine for the highly contagious respiratory virus.<\/p>\n<p>University of South Florida Health (USF Health) Morsani College of Medicine scientists recently worked with colleagues at the University of Arizona College of Pharmacy to identify several existing compounds that block replication of the COVID-19 virus (SARS-CoV-2) within <a href=\"https:\/\/medicalxpress.com\/tags\/human+cells\/\" rel=\"tag\" class=\"\">human cells<\/a> grown in the laboratory. The inhibitors all demonstrated potent chemical and structural interactions with a <a href=\"https:\/\/medicalxpress.com\/tags\/viral+protein\/\" rel=\"tag\" class=\"\">viral protein<\/a> critical to the virus\u2019s ability to proliferate.<\/p>\n<p>The research team\u2019s <a href=\"https:\/\/medicalxpress.com\/tags\/drug\/\" rel=\"tag\" class=\"\">drug<\/a> discovery study appeared June 15 in <i>Cell Research<\/i>, a high-impact Nature journal.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As the death toll from the COVID-19 pandemic mounts, scientists worldwide continue their push to develop effective treatments and a vaccine for the highly contagious respiratory virus. University of South Florida Health (USF Health) Morsani College of Medicine scientists recently worked with colleagues at the University of Arizona College of Pharmacy to identify several existing [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,1495],"tags":[],"class_list":["post-109599","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=109599"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109599\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=109599"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=109599"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=109599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}