{"id":109149,"date":"2020-06-26T06:22:17","date_gmt":"2020-06-26T13:22:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/06\/dynamics-of-dna-replication-revealed-at-the-nanoscale"},"modified":"2020-06-26T06:22:17","modified_gmt":"2020-06-26T13:22:17","slug":"dynamics-of-dna-replication-revealed-at-the-nanoscale","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/06\/dynamics-of-dna-replication-revealed-at-the-nanoscale","title":{"rendered":"Dynamics of DNA replication revealed at the nanoscale"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dynamics-of-dna-replication-revealed-at-the-nanoscale2.jpg\"><\/a><\/p>\n<p>DNA replication is a process of critical importance to the cell, and must be coordinated precisely to ensure that genomic information is duplicated once and only once during each cell cycle. Using super-resolution technology a University of Technology Sydney led team has directly visualized the process of DNA replication in single human cells.<\/p>\n<p>This is the first quantitative characterization to date of the spatio-temporal organization, morphology, and in situ epigenetic signatures of individual replication foci (RFi) in single human <a href=\"https:\/\/phys.org\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a> at the nanoscale.<\/p>\n<p>The results of the study, published in <i>PNAS<\/i> (<i>Proceedings of the National Academy of Sciences<\/i>) give new insight into a poorly understood area of DNA replication namely how replication origin sites are chosen from thousands of possible sites.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>DNA replication is a process of critical importance to the cell, and must be coordinated precisely to ensure that genomic information is duplicated once and only once during each cell cycle. Using super-resolution technology a University of Technology Sydney led team has directly visualized the process of DNA replication in single human cells. This is [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,4],"tags":[],"class_list":["post-109149","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=109149"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109149\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=109149"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=109149"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=109149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}