{"id":109020,"date":"2020-06-23T12:45:28","date_gmt":"2020-06-23T19:45:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/06\/scientists-produce-first-open-source-all-atom-models-of-covid-19-spike-protein"},"modified":"2020-06-23T12:45:28","modified_gmt":"2020-06-23T19:45:28","slug":"scientists-produce-first-open-source-all-atom-models-of-covid-19-spike-protein","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/06\/scientists-produce-first-open-source-all-atom-models-of-covid-19-spike-protein","title":{"rendered":"Scientists produce first open source all-atom models of COVID-19 \u2018spike\u2019 protein"},"content":{"rendered":"<p><\/p>\n<p><iframe style=\"display: block; margin: 0 auto; width: 100%; aspect-ratio: 4\/3; object-fit: contain;\" src=\"https:\/\/www.youtube.com\/embed\/1EhOWs-GZvQ?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope;\n   picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p>The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus disease 2019 (COVID-19). The \u201cspike\u201d or S protein facilitates viral entry into host cells.<\/p>\n<p>Now a group of researchers from Seoul National University in South Korea, University of Cambridge in UK, and Lehigh University in USA, have worked together to produce the first open-source all-atom models of a full-length S <a href=\"https:\/\/phys.org\/tags\/protein\/\" rel=\"tag\" class=\"\">protein<\/a>. The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.<\/p>\n<p>The details can be found in a <a href=\"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jpcb.0c04553\">paper<\/a>, \u201cDeveloping a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane\u201d just published online in The Journal of Physical Chemistry B.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus disease 2019 (COVID-19). The \u201cspike\u201d or S protein facilitates viral entry into host cells. Now a group of researchers from Seoul National University in South Korea, University of Cambridge in UK, and Lehigh University in USA, have worked together to produce the first [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19],"tags":[],"class_list":["post-109020","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109020","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=109020"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/109020\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=109020"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=109020"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=109020"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}