{"id":108702,"date":"2020-06-15T11:42:38","date_gmt":"2020-06-15T18:42:38","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/06\/diluting-blood-plasma-rejuvenates-tissue-reverses-aging-in-mice"},"modified":"2020-06-15T11:42:38","modified_gmt":"2020-06-15T18:42:38","slug":"diluting-blood-plasma-rejuvenates-tissue-reverses-aging-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/06\/diluting-blood-plasma-rejuvenates-tissue-reverses-aging-in-mice","title":{"rendered":"Diluting blood plasma rejuvenates tissue, reverses aging in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/diluting-blood-plasma-rejuvenates-tissue-reverses-aging-in-mice.jpg\"><\/a><\/p>\n<p>In 2005, University of California, Berkeley, researchers made the surprising discovery that making conjoined twins out of young and old mice\u2014such that they share blood and organs\u2014can rejuvenate tissues and reverse the signs of aging in the old mice. The finding sparked a flurry of research into whether a youngster\u2019s blood might contain special proteins or molecules that could serve as a \u201cfountain of youth\u201d for mice and humans alike.<\/p>\n<p>But a new study by the same team shows that similar age-reversing effects can be achieved by simply diluting the <a href=\"https:\/\/medicalxpress.com\/tags\/blood\/\" rel=\"tag\" class=\"\">blood<\/a> <a href=\"https:\/\/medicalxpress.com\/tags\/plasma\/\" rel=\"tag\" class=\"\">plasma<\/a> of old mice\u2014no <a href=\"https:\/\/medicalxpress.com\/tags\/young+blood\/\" rel=\"tag\" class=\"\">young blood<\/a> needed.<\/p>\n<p>In the study, the team found that replacing half of the blood plasma of old mice with a mixture of saline and albumin\u2014where the albumin simply replaces <a href=\"https:\/\/medicalxpress.com\/tags\/protein\/\" rel=\"tag\" class=\"\">protein<\/a> that was lost when the original blood plasma was removed\u2014has the same or stronger rejuvenation effects on the brain, liver and muscle than pairing with young mice or young blood exchange. Performing the same procedure on <a href=\"https:\/\/medicalxpress.com\/tags\/young+mice\/\" rel=\"tag\" class=\"\">young mice<\/a> had no detrimental effects on their health.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In 2005, University of California, Berkeley, researchers made the surprising discovery that making conjoined twins out of young and old mice\u2014such that they share blood and organs\u2014can rejuvenate tissues and reverse the signs of aging in the old mice. The finding sparked a flurry of research into whether a youngster\u2019s blood might contain special proteins [\u2026]<\/p>\n","protected":false},"author":426,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-108702","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/108702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/426"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=108702"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/108702\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=108702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=108702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=108702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}