{"id":108011,"date":"2020-06-01T10:22:17","date_gmt":"2020-06-01T17:22:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/06\/battling-parkinsons-disease"},"modified":"2020-06-01T10:22:17","modified_gmt":"2020-06-01T17:22:17","slug":"battling-parkinsons-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/06\/battling-parkinsons-disease","title":{"rendered":"Battling Parkinson\u2019s disease"},"content":{"rendered":"

<\/a><\/p>\n

Who has heard of mitochondrial medicine?<\/p>\n

\n

\u201cWe know that increased rates of mtDNA mutation cause premature aging,\u201d said Bruce Hay, Professor of biology and biological engineering at the California Institute of Technology. \u201cThis, coupled with the fact that mutant mtDNA accumulates in key tissues such as neurons and muscle that lose function as we age, suggests that if we could reduce the amount of mutant mtDNA, we could slow or reverse important aspects of aging.\u201d<\/p>\n

This brings us to the second major development relevant to mitochondria in disease \u2014 that genetic technology is now at a point where the targeted removal of the problem mitochondrial genes can become the basis for clinical intervention. This is the implication of research<\/a> that Hay and colleagues both at Caltech and the University of California at Los Angeles described in a paper published<\/a> in the journal Nature Communications<\/em>.<\/p>\n

Fixing body tissues by knocking out genes that prevent bad mitochondrial from being ousted in a timely fashion might sound like science fiction, but that\u2019s where things are going and it\u2019s part of a growing trend of what\u2019s being described as mitochondrial medicine<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Who has heard of mitochondrial medicine? \u201cWe know that increased rates of mtDNA mutation cause premature aging,\u201d said Bruce Hay, Professor of biology and biological engineering at the California Institute of Technology. \u201cThis, coupled with the fact that mutant mtDNA accumulates in key tissues such as neurons and muscle that lose function as we age, [\u2026]<\/p>\n","protected":false},"author":554,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,269,47],"tags":[],"class_list":["post-108011","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/108011","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/554"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=108011"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/108011\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=108011"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=108011"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=108011"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}