{"id":107693,"date":"2020-05-26T15:03:51","date_gmt":"2020-05-26T22:03:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/05\/an-under-researched-mechanism-in-the-fast-moving-field-of-epigenetics"},"modified":"2020-05-26T15:03:51","modified_gmt":"2020-05-26T22:03:51","slug":"an-under-researched-mechanism-in-the-fast-moving-field-of-epigenetics","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/05\/an-under-researched-mechanism-in-the-fast-moving-field-of-epigenetics","title":{"rendered":"An under-researched mechanism in the fast-moving field of epigenetics"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/an-under-researched-mechanism-in-the-fast-moving-field-of-epigenetics2.jpg\"><\/a><\/p>\n<p>A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice\u2014published this month in <i>Nature Communications <\/i>\u2014has shown.<\/p>\n<p>The study has implications for understanding how epigenetics works at a molecular level\u2014and down the track, the scientists hope the research will help them to investigate new treatments for <a href=\"https:\/\/phys.org\/tags\/blood\/\" rel=\"tag\" class=\"\">blood<\/a> disorders.<\/p>\n<p>\u201cEpigenetics looks at how non-permanent, acquired chemical marks on DNA determine whether or not particular <a href=\"https:\/\/phys.org\/tags\/genes\/\" rel=\"tag\" class=\"\">genes<\/a> are expressed,\u201d study leader and UNSW Professor Merlin Crossley says.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice\u2014published this month in Nature Communications \u2014has shown. The study has implications for understanding how epigenetics works at a molecular level\u2014and down the track, the scientists [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,412],"tags":[],"class_list":["post-107693","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=107693"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107693\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=107693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=107693"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=107693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}