{"id":107396,"date":"2020-05-21T07:02:21","date_gmt":"2020-05-21T14:02:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/05\/magnetic-core-shell-nanowires-as-mri-contrast-agents-for-cell-tracking"},"modified":"2020-05-21T07:02:21","modified_gmt":"2020-05-21T14:02:21","slug":"magnetic-core-shell-nanowires-as-mri-contrast-agents-for-cell-tracking","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/05\/magnetic-core-shell-nanowires-as-mri-contrast-agents-for-cell-tracking","title":{"rendered":"Magnetic core\u2013shell nanowires as MRI contrast agents for cell tracking"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/magnetic-core-shell-nanowires-as-mri-contrast-agents-for-cell-tracking2.jpg\"><\/a><\/p>\n<p>Interesting articles on theranostic iron nanowires. I\u2019m interested in watching all aspects of development of nanobots, because I think it may lead to new forms of treatments for superlongevity and superintelligence.<\/p>\n<p>Phys.org: Iron nanorobots go undercover to do surveillance on living cells in real time:<\/p>\n<p><a href=\"https:\/\/phys.org\/\">https:\/\/phys.org\/<\/a>\u2026\/2020\u201305-iron-nanorobots-undercover-surve\u2026<\/p>\n<hr>\n<p>Identifying the precise location of cells and their migration dynamics is of utmost importance for achieving the therapeutic potential of cells after implantation into a host. Magnetic resonance imaging is a suitable, non-invasive technique for cell monitoring when used in combination with contrast agents.<\/p>\n<p>This work shows that nanowires with an iron core and an iron oxide shell are excellent materials for this application, due to their customizable magnetic properties and biocompatibility. The longitudinal and transverse magnetic relaxivities of the core\u2013shell nanowires were evaluated at 1.5 T, revealing a high performance as T<sub>2<\/sub> contrast agents. Different levels of oxidation and various surface coatings were tested at 7 T. Their effects on the T<sub>2<\/sub> contrast were reflected in the tailored transverse relaxivities. Finally, the detection of nanowire-labeled breast cancer cells was demonstrated in T<sub>2<\/sub>-weighted images of cells implanted in both, in vitro in tissue-mimicking phantoms and in vivo in mouse brain. Labeling the cells with a nanowire concentration of 0.8 \u03bcg of Fe\/mL allowed the detection of 25 cells\/\u00b5L in vitro, diminishing the possibility of side effects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interesting articles on theranostic iron nanowires. I\u2019m interested in watching all aspects of development of nanobots, because I think it may lead to new forms of treatments for superlongevity and superintelligence. Phys.org: Iron nanorobots go undercover to do surveillance on living cells in real time: https:\/\/phys.org\/\u2026\/2020\u201305-iron-nanorobots-undercover-surve\u2026 Identifying the precise location of cells and their migration [\u2026]<\/p>\n","protected":false},"author":543,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,4,47,1511],"tags":[],"class_list":["post-107396","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-nanotechnology","category-neuroscience","category-surveillance"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107396","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/543"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=107396"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107396\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=107396"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=107396"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=107396"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}