{"id":107382,"date":"2020-05-21T00:08:53","date_gmt":"2020-05-21T07:08:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/05\/stem-cells-derived-from-fat"},"modified":"2020-05-21T00:08:53","modified_gmt":"2020-05-21T07:08:53","slug":"stem-cells-derived-from-fat","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/05\/stem-cells-derived-from-fat","title":{"rendered":"Stem Cells Derived From Fat"},"content":{"rendered":"<p><a class=\"blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/stem-cells-derived-from-fat.jpg\"><\/a><\/p>\n<p>Circa 2019 <span class=\"wp-smiley emoji emoji-face_with_colon_three\" title=\":3\">face_with_colon_three<\/span> <\/p>\n<hr>\n<p>Multipotent cells are critical to <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/regenerative-medicine\" title=\"Learn more about Regenerative Medicine from ScienceDirect's AI-generated Topic Pages\">regenerative medicine<\/a> and its associated deployment strategies. Localizing an abundant source of autologous, <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/adult-stem-cell\" title=\"Learn more about Adult Stem Cell from ScienceDirect's AI-generated Topic Pages\">adult stem cells<\/a> circumvents the immunological prohibitions of allogeneity and ethical dilemmas of embryologic stem cells, respectively. Classically, these cells have been described as <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/mesenchymal-stem-cell\" title=\"Learn more about Mesenchymal Stem Cell from ScienceDirect's AI-generated Topic Pages\">mesenchymal stem cells<\/a> (MSCs). In this chapter, we characterize <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/adipose-tissue\" title=\"Learn more about Adipose Tissue from ScienceDirect's AI-generated Topic Pages\">adipose tissue<\/a> as a unique source of MSCs because of its ubiquity, redundancy, and procurability. Specifically, lipoaspirates can be minimally processed to provide a heterogenous, cell-dense isolate \u2013 the stromal vascular fraction (SVF) \u2013 composed of terminally differentiated vessel-associated cell lines as well as putative <a href=\"https:\/\/www.sciencedirect.com\/topics\/biochemistry-genetics-and-molecular-biology\/progenitor-cell\" title=\"Learn more about Progenitor Cell from ScienceDirect's AI-generated Topic Pages\">progenitor cells<\/a>. These cells have been cultured and expanded, giving rise to a dynamic cell line termed adipose-derived <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/stromal-cell\" title=\"Learn more about Stromal Cell from ScienceDirect's AI-generated Topic Pages\">stromal cells<\/a> (ASCs). SVF and ASC cell isolates are often administered by standard clinical routes including parenteral, <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/topical-drug-administration\" title=\"Learn more about Topical Drug Administration from ScienceDirect's AI-generated Topic Pages\">topical application<\/a>, and local injection in the clinical translational studies of cardiovascular <a href=\"https:\/\/www.sciencedirect.com\/topics\/medicine-and-dentistry\/ischemia\" title=\"Learn more about Ischemia from ScienceDirect's AI-generated Topic Pages\">ischemia<\/a>, neurological injury, rheumatologic and orthopedic disease as well as advanced wound care and tissue engineering. These clinical applications raise safety concerns specific to administration, sequestration, and tumor growth augmentation. Further studies SVF and ASC cells are necessary to realize their potential in a regenerative medicine capacity.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Circa 2019 face_with_colon_three Multipotent cells are critical to regenerative medicine and its associated deployment strategies. Localizing an abundant source of autologous, adult stem cells circumvents the immunological prohibitions of allogeneity and ethical dilemmas of embryologic stem cells, respectively. Classically, these cells have been described as mesenchymal stem cells (MSCs). In this chapter, we characterize adipose [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,269],"tags":[],"class_list":["post-107382","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107382","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=107382"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107382\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=107382"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=107382"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=107382"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}