{"id":107123,"date":"2020-05-15T14:43:18","date_gmt":"2020-05-15T21:43:18","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/05\/vitamin-b3-revitalizes-energy-metabolism-in-muscle-disease"},"modified":"2020-05-15T14:43:18","modified_gmt":"2020-05-15T21:43:18","slug":"vitamin-b3-revitalizes-energy-metabolism-in-muscle-disease","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/05\/vitamin-b3-revitalizes-energy-metabolism-in-muscle-disease","title":{"rendered":"Vitamin B3 revitalizes energy metabolism in muscle disease"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/vitamin-b3-revitalizes-energy-metabolism-in-muscle-disease2.jpg\"><\/a><\/p>\n<p>An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effects in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments.<\/p>\n<p>Vitamin B3 forms have recently emerged as potent boosters of energy metabolism in rodents. These vitamins are precursors for NAD<sup>+<\/sup>, a molecular switch of metabolism between fasting and growth modes.<\/p>\n<p>As fasting has been shown promote health and longevity in for example mice, a variety of \u201cNAD boosters\u201d are being developed. However, whether actual NAD<sup>+<\/sup> deficiency exists in <a href=\"https:\/\/phys.org\/tags\/human+disease\/\" rel=\"tag\" class=\"\">human disease<\/a>, and whether NAD<sup>+<\/sup> boosters could have curative effects in patients with degenerative diseases, has remained elusive.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An international team of scientists, led by University of Helsinki reported that vitamin B3, niacin, has therapeutic effects in progressive muscle disease. Niacin delayed disease progression in patients with mitochondrial myopathy, a progressive disease with no previous curative treatments. Vitamin B3 forms have recently emerged as potent boosters of energy metabolism in rodents. These vitamins [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-107123","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107123","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=107123"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/107123\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=107123"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=107123"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=107123"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}