{"id":106994,"date":"2020-05-12T23:03:57","date_gmt":"2020-05-13T06:03:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/05\/scientists-show-mri-predicts-the-efficacy-of-a-stem-cell-therapy-for-brain-injury"},"modified":"2020-05-12T23:03:57","modified_gmt":"2020-05-13T06:03:57","slug":"scientists-show-mri-predicts-the-efficacy-of-a-stem-cell-therapy-for-brain-injury","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/05\/scientists-show-mri-predicts-the-efficacy-of-a-stem-cell-therapy-for-brain-injury","title":{"rendered":"Scientists show MRI predicts the efficacy of a stem cell therapy for brain injury"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-show-mri-predicts-the-efficacy-of-a-stem-cell-therapy-for-brain-injury.jpg\"><\/a><\/p>\n<p>Scientists at Sanford Burnham Prebys Medical Discovery Institute and Loma Linda University Health have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury\u2014a first-ever \u201cbiomarker\u201d for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve efficacy. The researchers expect to test the findings in a clinical trial evaluating the stem cell therapy in newborns who experience a brain injury during birth called perinatal hypoxic-ischemic brain injury (HII). The study was published in Cell Reports.<\/p>\n<p>\u201cIn order for stem cell therapies to benefit patients, we need to be thoughtful and scientific about who receives these treatments,\u201d says Evan Y. Snyder, M.D., Ph.D., professor and director of the Center for Stem Cells and Regenerative Medicine at Sanford Burnham Prebys, and corresponding study author. \u201cI am hopeful that MRI, which is already used during the course of care for these newborns, will help ensure that infants who experience HII get the best, most appropriate treatment possible. In the future, MRI could help guide the use of stem cells to treat\u2014or in some instances, not treat\u2014additional <a href=\"https:\/\/medicalxpress.com\/tags\/brain\/\" rel=\"tag\" class=\"\">brain<\/a> disorders such as spinal cord injury and stroke.\u201d<\/p>\n<p>Scientists now understand that, in many instances, human neural stem cells are therapeutic because they can protect living cells\u2014in contrast to \u201cre-animating\u201d or replacing nerve cells that are already dead. As a result, understanding the health of brain tissue prior to a <a href=\"https:\/\/medicalxpress.com\/tags\/stem+cell+transplant\/\" rel=\"tag\" class=\"\">stem cell transplant<\/a> is critical to the treatment\u2019s potential success. Tools that help predict the efficacy of neural stem cell therapy could increase the success of clinical trials, which are ongoing in people with Parkinson\u2019s disease, spinal cord injury and additional neurological conditions, while also sparing people who will not respond to treatment from an invasive procedure that offers false hope.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists at Sanford Burnham Prebys Medical Discovery Institute and Loma Linda University Health have demonstrated the promise of applying magnetic resonance imaging (MRI) to predict the efficacy of using human neural stem cells to treat a brain injury\u2014a first-ever \u201cbiomarker\u201d for regenerative medicine that could help personalize stem cell treatments for neurological disorders and improve [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-106994","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/106994","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=106994"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/106994\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=106994"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=106994"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=106994"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}