{"id":105792,"date":"2020-04-20T10:43:00","date_gmt":"2020-04-20T17:43:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/04\/turning-on-the-off-switch-in-cancer-cells"},"modified":"2020-04-20T10:43:00","modified_gmt":"2020-04-20T17:43:00","slug":"turning-on-the-off-switch-in-cancer-cells","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/04\/turning-on-the-off-switch-in-cancer-cells","title":{"rendered":"Turning on the \u2018off switch\u2019 in cancer cells"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/turning-on-the-off-switch-in-cancer-cells.jpg\"><\/a><\/p>\n<p>A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.<\/p>\n<p>The discovery marks a critical step toward developing a potential new class of anti\u2013<a href=\"https:\/\/medicalxpress.com\/tags\/cancer\/\" rel=\"tag\" class=\"\">cancer<\/a> drugs that enhance the activity of a prevalent family of tumor suppressor proteins, the authors say.<\/p>\n<p>The findings, which appear in the leading life sciences journal <i>Cell<\/i>, are less a story of what than how.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer. The discovery marks a critical step toward developing a potential new class of anti\u2013cancer [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-105792","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/105792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=105792"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/105792\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=105792"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=105792"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=105792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}