{"id":105791,"date":"2020-04-20T10:42:53","date_gmt":"2020-04-20T17:42:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/04\/new-therapeutic-options-for-multiple-sclerosis-in-sight"},"modified":"2020-04-20T10:42:53","modified_gmt":"2020-04-20T17:42:53","slug":"new-therapeutic-options-for-multiple-sclerosis-in-sight","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/04\/new-therapeutic-options-for-multiple-sclerosis-in-sight","title":{"rendered":"New therapeutic options for multiple sclerosis in sight"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-therapeutic-options-for-multiple-sclerosis-in-sight2.jpg\"><\/a><\/p>\n<p>Multiple sclerosis (MS) is known as \u201cthe disease with a thousand faces\u201d because symptoms and progression can vary dramatically from patient to patient. But every MS patient has one thing in common: Cells of their body\u2019s own immune system migrate to the brain, where they destroy the myelin sheath\u2014the protective outer layer of the nerve fibers. As a result, an electrical short circuit occurs, preventing the nerve signals from being transmitted properly.<\/p>\n<p><b>Many MS medications impair immune memory<\/b><\/p>\n<p>Researchers don\u2019t yet know exactly which <a href=\"https:\/\/medicalxpress.com\/tags\/immune+cells\/\" rel=\"tag\" class=\"\">immune cells<\/a> are involved in stripping away the myelin sheath. Autoreactive T and B <a href=\"https:\/\/medicalxpress.com\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a>, which wrongly identify the myelin sheath as a foreign body, travel to the brain and initiate the disease. \u201cUp until now, MS drugs have essentially targeted these T and B cells, both of which are part of the acquired <a href=\"https:\/\/medicalxpress.com\/tags\/immune+system\/\" rel=\"tag\" class=\"\">immune system<\/a>,\u201d says Dr. Alexander Mildner, a scientist at the Max Delbr\u00fcck Center for Molecular Medicine in the Helmholtz Association (MDC) and the senior author of the paper now published in Nature Immunology.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Multiple sclerosis (MS) is known as \u201cthe disease with a thousand faces\u201d because symptoms and progression can vary dramatically from patient to patient. But every MS patient has one thing in common: Cells of their body\u2019s own immune system migrate to the brain, where they destroy the myelin sheath\u2014the protective outer layer of the nerve [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-105791","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/105791","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=105791"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/105791\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=105791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=105791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=105791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}