{"id":105102,"date":"2020-04-10T14:43:10","date_gmt":"2020-04-10T21:43:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/04\/drug-shows-promise-in-reversing-kidney-damage-caused-by-lupus-update"},"modified":"2020-04-10T14:43:10","modified_gmt":"2020-04-10T21:43:10","slug":"drug-shows-promise-in-reversing-kidney-damage-caused-by-lupus-update","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/04\/drug-shows-promise-in-reversing-kidney-damage-caused-by-lupus-update","title":{"rendered":"Drug shows promise in reversing kidney damage caused by lupus (Update)"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/drug-shows-promise-in-reversing-kidney-damage-caused-by-lupus-update.jpg\"><\/a><\/p>\n<p>A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine.<\/p>\n<p>\u201cKidney damage affects about half of the patients with lupus, sometimes leading to renal failure with a requirement for dialysis or transplantation,\u201d said Joe Craft, the Paul B. Beeson Professor of Medicine (rheumatology) and professor of immunobiology. \u201cFinding what causes that damage is extremely important.\u201d<\/p>\n<p>Lupus is an autoimmune disease in which immune cells attack tissues in the body of the host, with kidneys being particularly susceptible in a condition called lupus nephritis. In lupus nephritis, the patient\u2019s own T cells infiltrate kidney tissue and trigger a decrease in oxygen, leading to <a href=\"https:\/\/medicalxpress.com\/tags\/tissue+damage\/\" rel=\"tag\" class=\"\">tissue damage<\/a> and potentially end-stage kidney disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine. \u201cKidney damage affects about half of the patients with lupus, sometimes leading to renal failure with a requirement for dialysis [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-105102","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/105102","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=105102"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/105102\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=105102"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=105102"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=105102"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}