{"id":10457,"date":"2014-03-25T14:16:39","date_gmt":"2014-03-25T21:16:39","guid":{"rendered":"http:\/\/lifeboat.com\/blog\/?p=10457"},"modified":"2017-04-25T04:15:24","modified_gmt":"2017-04-25T11:15:24","slug":"genetically-engineered-t-cells-used-as-a-weapon-against-hivaids","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2014\/03\/genetically-engineered-t-cells-used-as-a-weapon-against-hivaids","title":{"rendered":"Genetically Engineered T Cells Used as a Weapon Against HIV\/AIDS"},"content":{"rendered":"<p>Cameron Scott \u2014 Singularity Hub<br \/>\n<br \/> Carl June and his colleagues at the University of Pennsylvania have been making waves since they published some successes fighting leukemia with a revolutionary new method. They removed patients\u2019 T cells and genetically modified them to target and kill the cancer. When the T cells were reintroduced into the patients\u2019 bloodstreams, their cancer was often sent into complete remission.<\/p>\n<p>Could similar modifications to the immune system\u2019s fighter pilots provide revolutionary cures for other cancers and even other diseases?<\/p>\n<p>The U. Penn researchers are applying a similar technique to that other hardest-to-treat disease, HIV\/AIDS. They recently <a href=\"http:\/\/10.1056\/NEJMoa1300662\">completed<\/a> a Phase 1 clinical trial in which they removed HIV-positive patients\u2019 T cells and genetically modified a portion of them to include a rare HIV-resistant genetic mutation of the CCR5 gene (called delta 32).<\/p>\n<p><a href=\"http:\/\/singularityhub.com\/2014\/03\/23\/genetically-engineered-t-cells-targeted-as-a-weapon-against-hivaids\/\" target=\"_blank\">Read more<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cameron Scott \u2014 Singularity Hub Carl June and his colleagues at the University of Pennsylvania have been making waves since they published some successes fighting leukemia with a revolutionary new method. They removed patients\u2019 T cells and genetically modified them to target and kill the cancer. When the T cells were reintroduced into the patients\u2019 [\u2026]<\/p>\n","protected":false},"author":76,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-10457","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/10457","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/76"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=10457"}],"version-history":[{"count":1,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/10457\/revisions"}],"predecessor-version":[{"id":47161,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/10457\/revisions\/47161"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=10457"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=10457"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=10457"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}