{"id":104267,"date":"2020-03-25T16:43:00","date_gmt":"2020-03-25T23:43:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/03\/gene-therapy-for-sickle-cell-anemia-looks-promising-but-its-riddled-with-controversy"},"modified":"2020-03-25T16:43:00","modified_gmt":"2020-03-25T23:43:00","slug":"gene-therapy-for-sickle-cell-anemia-looks-promising-but-its-riddled-with-controversy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/03\/gene-therapy-for-sickle-cell-anemia-looks-promising-but-its-riddled-with-controversy","title":{"rendered":"Gene Therapy for Sickle-Cell Anemia Looks Promising\u2014but It\u2019s Riddled With Controversy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/gene-therapy-for-sickle-cell-anemia-looks-promising-but-its-riddled-with-controversy2.jpg\"><\/a><\/p>\n<p><b>The Curious Case of Sickle-Cell Anemia<\/b><\/p>\n<p>Even those uninterested in biology have likely heard of the disorder. Sickle-cell anemia holds the crown as the first genetic disorder to be traced to its molecular roots nearly a hundred years ago.<\/p>\n<p>The root of the disorder is a single genetic mutation that drastically changes the structure of the oxygen-carrying protein, beta-globin, in red blood cells. The result is that the cells, rather than forming their usual slick disc-shape, turn into jagged, sickle-shaped daggers that damage blood vessels or block them altogether. The symptoms aren\u2019t always uniform; rather, they come in \u201ccrisis episodes\u201d during which the pain becomes nearly intolerable.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Curious Case of Sickle-Cell Anemia Even those uninterested in biology have likely heard of the disorder. Sickle-cell anemia holds the crown as the first genetic disorder to be traced to its molecular roots nearly a hundred years ago. The root of the disorder is a single genetic mutation that drastically changes the structure of [\u2026]<\/p>\n","protected":false},"author":556,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-104267","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/104267","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/556"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=104267"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/104267\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=104267"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=104267"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=104267"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}