{"id":103984,"date":"2020-03-19T13:04:33","date_gmt":"2020-03-19T20:04:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/03\/nih-study-provides-genetic-insights-into-osteosarcoma-in-children"},"modified":"2020-03-19T13:04:33","modified_gmt":"2020-03-19T20:04:33","slug":"nih-study-provides-genetic-insights-into-osteosarcoma-in-children","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/03\/nih-study-provides-genetic-insights-into-osteosarcoma-in-children","title":{"rendered":"NIH study provides genetic insights into osteosarcoma in children"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/nih-study-provides-genetic-insights-into-osteosarcoma-in-children2.jpg\"><\/a><\/p>\n<p>A study by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common cancerous bone tumor of children and adolescents. The researchers found that more people with osteosarcoma carry harmful, or likely harmful, variants in known cancer-susceptibility genes than people without osteosarcoma. This finding has implications for genetic testing of children with osteosarcoma, as well as their families.<\/p>\n<p>The study was published March 19, 2020, in <em>JAMA Oncology<\/em>.<\/p>\n<p>\u201cWith this study, we wanted to find out how many people with osteosarcoma may have been at high risk for it because of their genetics,\u201d said Lisa Mirabello, Ph.D., of NCI\u2019s Division of Cancer Epidemiology and Genetics (DCEG), who led the research. \u201cWe not only learned that at least a quarter of the people in the study with osteosarcoma had a variant in a gene known to predispose someone to cancer, we also uncovered variants that had never before been associated with this cancer.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health, offers new insight into genetic alterations associated with osteosarcoma, the most common cancerous bone tumor of children and adolescents. The researchers found that more people with osteosarcoma carry harmful, or likely harmful, variants in known cancer-susceptibility genes than [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,1495],"tags":[],"class_list":["post-103984","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/103984","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=103984"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/103984\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=103984"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=103984"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=103984"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}