{"id":103860,"date":"2020-03-17T06:44:24","date_gmt":"2020-03-17T13:44:24","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/03\/new-crispr-tool-fixes-cftr-mutations-in-cf-patients-stem-cells-study-finds"},"modified":"2020-03-17T06:44:24","modified_gmt":"2020-03-17T13:44:24","slug":"new-crispr-tool-fixes-cftr-mutations-in-cf-patients-stem-cells-study-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/03\/new-crispr-tool-fixes-cftr-mutations-in-cf-patients-stem-cells-study-finds","title":{"rendered":"New CRISPR Tool Fixes CFTR Mutations in CF Patients\u2019 Stem Cells, Study Finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/new-crispr-tool-fixes-cftr-mutations-in-cf-patients-stem-cells-study-finds2.jpg\"><\/a><\/p>\n<p>A new variation of the gene-editing technology CRISPR-Cas9 can correct mutations in the <em>CFTR <\/em>gene \u2014 the genetic cause of <a href=\"https:\/\/cysticfibrosisnewstoday.com\/cystic-fibrosis-overview\/\">cystic fibrosis<\/a> (CF) \u2014 in stem cells from CF patients, a study shows.<\/p>\n<p>The new approach has the ability to correct mutations without the need to excise the affected region, the researchers said.<\/p>\n<p>The study, \u201c<a href=\"https:\/\/www.cell.com\/cell-stem-cell\/fulltext\/S1934-5909(20)30019-9\">CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank,<\/a>\u201d was published in the journal <a href=\"https:\/\/www.cell.com\/cell-stem-cell\/home\"><em>Cell Stem Cell<\/em>.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new variation of the gene-editing technology CRISPR-Cas9 can correct mutations in the CFTR gene \u2014 the genetic cause of cystic fibrosis (CF) \u2014 in stem cells from CF patients, a study shows. The new approach has the ability to correct mutations without the need to excise the affected region, the researchers said. The study, [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-103860","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/103860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=103860"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/103860\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=103860"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=103860"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=103860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}