{"id":103287,"date":"2020-03-04T23:05:00","date_gmt":"2020-03-05T07:05:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/03\/scientists-discover-new-repair-mechanism-for-alcohol-induced-dna-damage"},"modified":"2020-03-04T23:05:00","modified_gmt":"2020-03-05T07:05:00","slug":"scientists-discover-new-repair-mechanism-for-alcohol-induced-dna-damage","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/03\/scientists-discover-new-repair-mechanism-for-alcohol-induced-dna-damage","title":{"rendered":"Scientists discover new repair mechanism for alcohol-induced DNA damage"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-discover-new-repair-mechanism-for-alcohol-induced-dna-damage2.jpg\"><\/a><\/p>\n<p>Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. That knowledge underlines the link between alcohol consumption and cancer. The research groups of Puck Knipscheer and Ketan J. Patel worked together on this study and published the results in the scientific journal <i>Nature<\/i> on the 4th of March.<\/p>\n<p>Our DNA is a daily target for a barrage of damage caused by radiation or toxic substances such as alcohol. When alcohol is metabolized, acetaldehyde is formed. Acetaldehyde causes a dangerous kind of DNA damage\u2014the interstrand crosslink (ICL)\u2014that sticks together the two strands of the DNA. As a result, it obstructs <a href=\"https:\/\/phys.org\/tags\/cell+division\/\" rel=\"tag\" class=\"\">cell division<\/a> and protein production. Ultimately, an accumulation of ICL damage may lead to cell death and cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. That knowledge underlines the link between alcohol consumption and cancer. The research groups of [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-103287","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/103287","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=103287"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/103287\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=103287"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=103287"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=103287"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}