{"id":102892,"date":"2020-02-26T09:42:49","date_gmt":"2020-02-26T17:42:49","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/02\/gene-editing-is-more-error-prone-than-thought-new-findings-suggest"},"modified":"2020-02-27T11:36:13","modified_gmt":"2020-02-27T19:36:13","slug":"gene-editing-is-more-error-prone-than-thought-new-findings-suggest","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/02\/gene-editing-is-more-error-prone-than-thought-new-findings-suggest","title":{"rendered":"Gene-editing is more error-prone than thought, new findings suggest"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/gene-editing-is-more-error-prone-than-thought-new-findings-suggest4.jpg\"><\/a><\/p>\n<p>The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences (PNAS). In describing these findings the researchers called such oversights \u201cserious pitfalls\u201d of gene editing (Skryabin et al., 2020). In all, the new results suggest that gene-editing is more error-prone than thought and, further, that identifying and discarding defective and unwanted outcomes is not as easy as generally supposed.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" alt=\"Gene-editing is more error-prone than thought, new findings suggest\" src=\"https:\/\/lifeboat.com\/blog.images\/gene-editing-is-more-error-prone-than-thought-new-findings-suggest6.jpg\" data-srcset=\"\/image.axd?picture=2020%2f2%2fCRISPR.jpg&amp;ts=20200226074008&amp;ri=590 590w, \/image.axd?picture=2020%2f2%2fCRISPR.jpg&amp;ts=20200226074008&amp;ri=550 550w, \/image.axd?picture=2020%2f2%2fCRISPR.jpg&amp;ts=20200226074008&amp;ri=450 450w\" data-sizes=\"(min-width: 630px) 590px, (min-width: 480px) calc(100vw - 40px), calc(100vw - 30px)\" title=\"Gene-editing is more error-prone than thought, new findings suggest\" width=\"590\" height=\"393\"><\/p>\n<p><center><em> CRISPR Enzyme on DNA (Photo: MIT News) <\/em><\/center><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences (PNAS). In describing these findings the researchers called such oversights \u201cserious pitfalls\u201d of gene editing (Skryabin et al., 2020). In all, the new results [\u2026]<\/p>\n","protected":false},"author":501,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-102892","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/102892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/501"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=102892"}],"version-history":[{"count":4,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/102892\/revisions"}],"predecessor-version":[{"id":102950,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/102892\/revisions\/102950"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=102892"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=102892"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=102892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}