{"id":101584,"date":"2020-01-29T15:46:53","date_gmt":"2020-01-29T23:46:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/01\/car-t-treatments-could-have-fewer-side-effects-than-other-cancer-immunotherapies"},"modified":"2020-01-29T15:46:53","modified_gmt":"2020-01-29T23:46:53","slug":"car-t-treatments-could-have-fewer-side-effects-than-other-cancer-immunotherapies","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/01\/car-t-treatments-could-have-fewer-side-effects-than-other-cancer-immunotherapies","title":{"rendered":"CAR T treatments could have fewer side effects than other cancer immunotherapies"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/car-t-treatments-could-have-fewer-side-effects-than-other-cancer-immunotherapies.jpg\"><\/a><\/p>\n<p>New cancer immunotherapies involve extracting a patient\u2019s T cells and genetically engineering them so they will recognize and attack tumors. This technique is a true medical breakthrough, with an increasing number of leukemia and lymphoma patients experiencing complete remissions since CAR T therapy was FDA approved in 2017.<\/p>\n<p>This type of therapy is not without challenges, however. Engineering a patient\u2019s T <a href=\"https:\/\/phys.org\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a> is laborious and expensive. And when successful, the alterations to the immune system immediately make patients very sick for a short period of time, with symptoms including fever, nausea and neurological effects.<\/p>\n<p>Now, University of Pennsylvania researchers have demonstrated a new engineering technique that, because it is less toxic to the T cells, could enable a different mechanism for altering the way they recognize cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>New cancer immunotherapies involve extracting a patient\u2019s T cells and genetically engineering them so they will recognize and attack tumors. This technique is a true medical breakthrough, with an increasing number of leukemia and lymphoma patients experiencing complete remissions since CAR T therapy was FDA approved in 2017. This type of therapy is not without [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38,412],"tags":[],"class_list":["post-101584","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/101584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=101584"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/101584\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=101584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=101584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=101584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}