{"id":101518,"date":"2020-01-28T12:05:01","date_gmt":"2020-01-28T20:05:01","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2020\/01\/nanoparticle-chomps-away-plaques-that-cause-heart-attacks"},"modified":"2020-01-28T12:05:01","modified_gmt":"2020-01-28T20:05:01","slug":"nanoparticle-chomps-away-plaques-that-cause-heart-attacks","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2020\/01\/nanoparticle-chomps-away-plaques-that-cause-heart-attacks","title":{"rendered":"Nanoparticle chomps away plaques that cause heart attacks"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/nanoparticle-chomps-away-plaques-that-cause-heart-attacks2.jpg\"><\/a><\/p>\n<p>Michigan State University and Stanford University scientists have invented a nanoparticle that eats away\u2014from the inside out\u2014portions of plaques that cause heart attacks.<\/p>\n<p>Bryan Smith, associate professor of biomedical engineering at MSU, and a team of scientists created a \u201cTrojan Horse\u201d nanoparticle that can be directed to eat debris, reducing and stabilizing plaque. The discovery could be a potential treatment for atherosclerosis, a leading cause of death in the United States.<\/p>\n<p>The results, published in the current issue of <i>Nature Nanotechnology<\/i>, showcases the nanoparticle that homes in on <a href=\"https:\/\/phys.org\/tags\/atherosclerotic+plaque\/\" rel=\"tag\" class=\"\">atherosclerotic plaque<\/a> due to its high selectivity to a particular immune cell type\u2014monocytes and macrophages. Once inside the macrophages in those plaques, it delivers a drug agent that stimulates the cell to engulf and eat cellular debris. Basically, it removes the diseased\/dead <a href=\"https:\/\/phys.org\/tags\/cells\/\" rel=\"tag\" class=\"\">cells<\/a> in the plaque core. By reinvigorating the macrophages, <a href=\"https:\/\/phys.org\/tags\/plaque\/\" rel=\"tag\" class=\"\">plaque<\/a> size is reduced and stabilized.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Michigan State University and Stanford University scientists have invented a nanoparticle that eats away\u2014from the inside out\u2014portions of plaques that cause heart attacks. Bryan Smith, associate professor of biomedical engineering at MSU, and a team of scientists created a \u201cTrojan Horse\u201d nanoparticle that can be directed to eat debris, reducing and stabilizing plaque. The discovery [\u2026]<\/p>\n","protected":false},"author":547,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38,15,4],"tags":[],"class_list":["post-101518","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering","category-habitats","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/101518","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/547"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=101518"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/101518\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=101518"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=101518"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=101518"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}