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Jan 23, 2020

Revel Pharma to repair collagen damaged by aging and diabetes using designer enzymes

Posted by in categories: biotech/medical, life extension, neuroscience

For the past 10 years, Yale Professors David Spiegel and Jason Crawford have been working on tools to enable the development of glucosepane-cleaving drugs. Kizoo Technology Capital investors say now is the time to advance this groundbreaking research toward the clinic and are leading funding of a new company, Revel Pharmaceuticals Inc., founded by Drs. David Spiegel, Jason Crawford, and Aaron Cravens.

Kizoo leads the seed financing round at Revel, with Oculus co-founder Michael Antonov participating. SENS Research Foundation provided funding to the YaleGlycoSENS group for several years.

The long-lived collagen proteins that give structure to our arteries, skin, and other tissues are continuously exposed to blood sugar and other highly reactive molecules necessary for life. Occasionally, these sugar molecules will bind to collagen and form toxic crosslinks that alter the physical properties of tissues and cause inflammation. As a result, tissues slowly stiffen with aging, leading to rising systolic blood pressure, skin aging, kidney damage, and increased risk of stroke and other damage to the brain.

Jan 23, 2020

Machine learning on the edge

Posted by in category: robotics/AI

In a recent IEEE Spectrum article, learn how engineers are taking machine learning to the smallest microprocessors, while facing challenges in energy consumption, compressing neural networks, and privacy practices. #tinyML #neuralnetworks #machinelearning


IN FEBRUARY, a group of researchers from Google, Microsoft, Qualcomm, Samsung, and half a dozen universities will gather in San Jose, Calif., to discuss the challenge of bringing machine learning to the farthest edge of the network, specifically microprocessors running on sensors or other battery-powered devices.

Jan 23, 2020

A “Superfood” as the Next Antimalarial?

Posted by in category: biotech/medical

Researchers have found that aҫaí berry extracts can reduce parasites in the blood and prolong the survival of infected mice.


Thankfully, researchers at the University of Campinas (UNICAMP) in Brazil are actively searching for new treatment options and have stumbled upon some interesting new data that could prove extremely useful in the fight against this persistent parasitic infection.

Amazingly, the researchers found antimalarial in a seemingly unlikely candidate, the aҫaí berry. Findings from the new study—published recently in ACS Omega through an article titled “Chemical Genomic Profiling Unveils the in vitro and in vivo Antiplasmodial Mechanism of Açaı́ (Euterpe oleracea Mart.) Polyphenols”—showed that berry extracts can reduce parasites in the blood and prolong the survival of infected mice.

Continue reading “A ‘Superfood’ as the Next Antimalarial?” »

Jan 23, 2020

Mum No More: 3D Printed Vocal Tract Lets Mummy Speak

Posted by in categories: 3D printing, biotech/medical, education

The coffin that holds the mummified body of the ancient Egyptian Nesyamun, who lived around 1100 B.C., expresses the man’s desire for his voice to live on. Now, 3,000 years after his death, that wish has come true. Using a 3D-printed replica of Nesyamun’s vocal tract and an electronic larynx, researchers in the UK have synthesized the dead man’s voice. Listen to it here:

Jan 23, 2020

How 3D Printing, Vertical Farming, and Materials Science Are Overhauling Food

Posted by in categories: 3D printing, food, robotics/AI, science

Within the next 10 years, what we eat and how it’s grown will be fundamentally transformed.


And converging exponential technologies—from materials science to AI-driven digital agriculture—are not slowing down. Today’s breakthroughs will soon allow our planet to boost its food production by nearly 70 percent, using a fraction of the real estate and resources, to feed 9 billion by mid-century.

What you consume, how it was grown, and how it will end up in your stomach will all ride the wave of converging exponentials, revolutionizing the most basic of human needs.

Continue reading “How 3D Printing, Vertical Farming, and Materials Science Are Overhauling Food” »

Jan 23, 2020

Priority to US24924494A

Posted by in categories: biotech/medical, information science, life extension

A method and apparatus for ameliorating the aging process and the effects of aging and maintaining the integrity of health is provided. The method includes subjecting biological systems to alternating and steady magnetic fields having flux densities ranging from 10-6 gauss to 10-20 gauss and frequencies from 0 Hertz to 1014 Hertz. The calculation is made with reference to the equation mc2 =Bvlq, where m=mass; c=speed of light; B=magnetic flux density; v=inertial velocity of the mass contained in l; l=length of the conductive body; q=unity. The process begins by targeting the larger targets first and then diminishing the field magnitude slowly and incrementally according to the targets. The frequency when AC is indicated is calculated with the cyclotron resonance formula, fc =qB/(2πm). The apparatus includes a specially constructed pool or tub for generating the specific magnetic flux necessary for treatment. Orientation of the patient with reference to North, South, East and West is varied. The earth’s position in relation to the sun is taken into account. The patient may be in an upright, prone or swimming position depending on the specific treatment scheme.

Jan 23, 2020

🏺A while before the Sun was born

Posted by in categories: asteroid/comet impacts, existential risks, particle physics

Fyodor R.

Scientists recently identified the oldest material on Earth: stardust that’s 7 billion years old, tucked away in a massive, rocky meteorite that struck our planet half a century ago.

🏺Stardust

Continue reading “🏺A while before the Sun was born” »

Jan 23, 2020

Helium-3 mining on the lunar surface

Posted by in categories: nuclear energy, space travel

The idea of harvesting a clean and efficient form of energy from the Moon has stimulated science fiction and fact in recent decades. Unlike Earth, which is protected by its magnetic field, the Moon has been bombarded with large quantities of Helium-3 by the solar wind. It is thought that this isotope could provide safer nuclear energy in a fusion reactor, since it is not radioactive and would not produce dangerous waste products.

The Apollo programme’s own geologist, Harrison Schmidt, has repeatedly made the argument for Helium-3 mining, whilst Gerald Kulcinski at the University of Wisconsin-Madison is another leading proponent. He has created a small reactor at the Fusion Technology Institute, but so far it has not been possible to create the helium fusion reaction with a net power output.

This has not stopped the search for Helium-3 from being a motivating factor in space exploration, however. Apart from the traditional space-faring nations, the India has previously indicated its interest in mining the lunar surface. The use of Moon resources was also part of Newt Gingrich’s unsuccessful candidacy for the Republican party’s nomination for the US presidency in 2012.

Jan 23, 2020

Stimulating Blood Vessel Growth Using FGF1 May Hold Promise for PD, Company Says

Posted by in categories: biotech/medical, neuroscience

Stimulating the growth of blood vessels in the brain through the use of fibroblast growth factor 1 (FGF1) may hold promise as a strategy for treating Parkinson’s disease, according to a white paper released by Zhittya Genesis Medicine (ZGM). Clinical trials testing this theory are being planned.

The white paper is titled “Parkinson’s Disease: Therapeutic Angiogenesis as a Disease Modifying, Breakthrough Therapy?”

Jan 23, 2020

Noisy signals strengthen human brainwaves

Posted by in category: neuroscience

‘Stochastic resonance’ seen in the brain’s information processing area.