Lifeboat Foundation

In biotech these days, CRISPR/Cas9 is a hot topic, because of its utility as a precise gene editing tool. Before humans repurposed it, CRISPR/Cas9 was a sort of internal immune system bacteria use to defend themselves against phages, or viruses that infect bacteria, by slicing up the phages’ DNA.

Scientists at Emory University School of Medicine and the Max Planck Unit for the Science of Pathogens have found that the “scissors” component of CRISPR/Cas9 sometimes gets stuck.

Cas9, an enzyme that cuts DNA, can also block gene activity without doing any cutting. In the pathogenic bacterium Francisella novicida, Cas9 regulates genes that need to be shut off for the bacteria to cause disease.

The successful treatment shows “precision medicine” can be expanded beyond cancers, where it has shown the greatest promise, scientists reported Monday.

Some mice receiving a therapy that includes CRISPR gene editing appear to have been cured of HIV, but safety concerns must be overcome before human trials.

Can space exploration help us protect biodiversity on Earth, and what cautions does our history in space offer?

The ways in which the communities of bacteria living within our bodies influence our overall well-being are becoming better understood all the time, and with that better understanding comes potential new ways to intervene for better health outcomes. Adding to this is a new discovery by researchers in Melbourne, who have described how a healthy microbiome can boost the activity of killer immune cells that are vital to fighting off infections and cancer.

Developing a clean (carbon-free), safe and economical form of energy, with abundant, globally distributed fuel to serve humanity for tens of thousands of years: Fusion.

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“I Will Be Glad” from Ziggy Marley’s 7th solo studio album, ‘Rebellion Rises’! Stream/download/buy the full album now at http://smarturl.it/rebellionrises

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Ziggy Marley & The Melody Makers perform Bob Marley’s classic hit “Natural Mystic” live in concert at the House Of Blues in Chicago, Illinois on September 9, 1999!

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Robots like the Pointman Tactical Robot and the iRobot Negotiator are already capable of entering buildings, climbing stairs and moving over obstacles to search buildings. Future versions are more likely to be armed, have more advanced sensors, hold greater autonomy, and be classified.

More agile humanoid (or animal-like) versions of these robots could be used to clear buildings of booby traps and enemy fighters seeking to ambush troops.