Menu

Blog

Page 7403

Aug 6, 2019

CRISPR Gene Editing Is Being Tested in Human Patients. Here’s What You Need to Know

Posted by in categories: bioengineering, biotech/medical, genetics

The trial is just one of a few underway to test the powerful CRISPR technology around the world. One of the most promising, for example, is studying whether gene editing can treat, and effectively cure, blood disorders such as beta thalassemia and sickle cell anemia.

In beta thalassemia, the hemoglobin part of red blood cells, which is supposed to pick up oxygen from the lungs and distribute it to the cells in the rest of the body, doesn’t work properly. Patients need to be transfused with donors blood regularly, and even with these transfusions, complications can occur if the dose isn’t right and iron levels in the blood cells spike, which can lead to organ damage and even death. In sickle cell disease, a mutation in the gene that makes hemoglobin causes the red blood cells to collapse into a sickle shape, which makes it more difficult for the cells to flow smoothly through the body’s arteries and veins. Blockages caused by the misshapen blood cells can lead to severe pain and strokes.

The biotech company CRISPR Therapeutics, founded by one of the technology’s co-developers, has engineered a solution to treat both conditions that relies on genetic modifications connected to the production of fetal hemoglobin. Normally fetal hemoglobin, which provides the developing fetus with oxygen via the blood while in utero, is shut off about six months after birth, and genes for adult hemoglobin are turned on. While it’s not clear why adult hemoglobin replaces the fetal version, researchers say that they have not seen any significant differences between the two types when it comes to the ability to transport oxygen to the body’s cells. However, since the genes for adult hemoglobin don’t produce healthy red blood cells in people with beta thalassemia and sickle cell disease, one treatment strategy is to introduce genetic changes that turn on fetal hemoglobin again.

Aug 6, 2019

Watch Live Tuesday: 2 Rocket Launches and a Space Station Cargo Ship’s Departure

Posted by in categories: robotics/AI, satellites

Today (Aug. 6) is going to be a big day in space!

After a Cygnus cargo spacecraft departs the International Space Station this afternoon, SpaceX and Arianespace will be launching a total of three new communications satellites into orbit. You can watch all three events live here at Space.com.

First, the Cygnus cargo ship will undock from the space station at 12:15 p.m. EDT (1615 GMT). NASA astronauts Nick Hague and Christina Koch will use the station’s Canadarm2 robotic arm to release the vessel into the vacuum of space. NASA TV will provide live coverage of the send-off beginning 15 minutes prior to its departure.

Aug 6, 2019

The evolution of Emotet: How to protect your network

Posted by in categories: cybercrime/malcode, evolution, finance

With over 350,000 new malware samples emerging every day, it’s difficult for any one strain of malware to make a name for itself. Any single malware sample whose name you know — be it Mirai, WannaCry, or NotPetya — speaks to a trail of devastation.

In 2019, people are also hearing another name: Emotet.

But Emotet has been around in one form or another since 2014, and its first major resurgence was in 2017. In the beginning, Emotet was just one trojan among many — a particularly run-of-the-mill banking trojan that did some damage before being researched, understood, and dismissed in a flurry of signature updates.

Aug 6, 2019

Where Death Ends and Cyborgs Begin, With Futurist Zoltan Istvan

Posted by in categories: biotech/medical, cyborgs, education, finance, life extension, singularity, transhumanism

I’m excited to share my new 1 hour interview at Singularity University radio with Steven Parton. Also, check out Singularity Hub and the write-up they did of the interview. We talk all things transhumanism, longevity, Cyborgs, and the future:


Singularity University, Singularity Hub, Singularity Summit, SU Labs, Singularity Labs, Exponential Medicine, Exponential Finance and all associated logos and design elements are trademarks and/or service marks of Singularity Education Group.

© 2019 Singularity Education Group. All Rights Reserved.

Continue reading “Where Death Ends and Cyborgs Begin, With Futurist Zoltan Istvan” »

Aug 6, 2019

Reversing Age-Related Vision Loss Using Cellular Reprogramming

Posted by in categories: genetics, life extension

Today, we want to draw attention to a new study that shows how partial cellular reprogramming was able to reverse cellular aging and address age- and injury-induced blindness in mice.

Epigenetic alterations

One of the proposed reasons we age is the changes to gene expression that our cells experience as we get older; these are known as epigenetic alterations. These alterations cause harmful changes to cellular function and gradually shift our cells from a youthful to aged state.

Aug 6, 2019

Goldman Sachs is spending $100 million to shave milliseconds off stock trades

Posted by in category: finance

Goldman Sachs is taking aim at the world’s biggest quant hedge funds.

The investment bank recently approved a three-year plan to spend more than $100 million to overhaul its stock trading platform, according to Mike Blum, a Goldman partner and chief technology officer of electronic trading.

The project, named Atlas after the Greek God, is meant to accelerate the shift Goldman has been making since realizing in 2014 it was falling behind in Wall Street’s equities technological arms race. Huge quant funds like Renaissance Technologies and Two Sigma are among the most demanding of clients from a technology perspective, and competitors including Morgan Stanley and J.P. Morgan have been jockeying to serve these money managers.

Aug 5, 2019

A Multimillionaire Surveillance Dealer Steps Out Of The Shadows… And His $9 Million WhatsApp Hacking Van

Posted by in categories: cybercrime/malcode, mobile phones, surveillance

He can hack your WhatsApp, find out where you are in 15 minutes and monitor your iPhone. But Tal Dilian says he’s one of the good guys. It’s badly-behaved governments who should be in trouble, not the $12 billion industry he’s come to represent.

Aug 5, 2019

Embracing the Immaterial Universe

Posted by in category: alien life

For over four hundred years, Western civilization has chosen science as its source of truths and wisdom about the mysteries of life. Allegorically, we may picture the wisdom of the universe as resembling a large mountain. We scale the mountain as we acquire knowledge. Our drive to reach the top of that mountain is fueled by the notion that with knowledge we may become ‘masters’ of our universe. Conjure the image of the all-knowing guru seated atop the mountain.

Scientists are professional seekers, forging the path up the “mountain of knowledge.” Their search takes them into the uncharted unknowns of the universe. With each scientific discovery, humanity gains a better foothold in scaling the mountain. Ascension is paved one scientific discovery at a time. Along its path, science occasionally encounters a fork in the road. Do they take the left turn or the right? When confronted with this dilemma, the direction chosen by science is determined by the consensus of scientists interpreting the acquired facts, as they are understood at the time.

Alt text hereAlong its path, science occasionally encounters a fork in the road.

Aug 5, 2019

Beijing is prepping for a massacre in Hong Kong: time for the West to put human rights ahead of free trade

Posted by in category: economics

After eight weeks of huge Hong Kong street protests against Beijing’s rule, the People’s Republic is massing police and soldiers just across the border. Message: If the protesters don’t quit, a bloodbath is coming.

Beijing has also started denouncing the protests as the work of American provocateurs. That’s so the regime can paint its Tiananmen Square-style crackdown as a battle against “foreign influence,” not a smashing of Chinese people who decided all on their own that they’d rather be free.

A quarter-century ago, the West wagered that welcoming China into the world economy would seduce the Communist Party into allowing ever-more freedom. That bet’s been lost.

Aug 5, 2019

Buy organic food to help curb global insect collapse, say scientists

Posted by in categories: food, sustainability

Buying organic food is among the actions people can take to curb the global decline in insects, according to leading scientists. Urging political action to slash pesticide use on conventional farms is another, say environmentalists.