Lifeboat Foundation

Scientists at the Morgridge Institute for Research have isolated a natural chemical that acts as a potent kryptonite against schistosomes, the parasitic worms that burrow through human skin and cause devastating health problems.

A research team led by Morgridge investigator Phillip Newmark reported in today’s (Oct. 17, 2019) issue of PLOS Biology the successful characterization of this chemical, which could lead to new ways to fight the neglected tropical disease schistosomiasis. This disease, caused by schistosome infection, affects more than 240 million people in Africa, Asia and parts of South America.

In this work the Newmark team focused on a phase of the schistosome life cycle that’s an intriguing target for preventing infection. Schistosomes seek out freshwater snails as hosts in order to produce millions of tiny fork-tailed creatures called cercaria, which are unleashed in the water and seek out mammals to infect. Their frenzied swimming allows them to penetrate human skin in minutes.

Scientists who are trying to save species at the brink of extinction are finding help in an unexpected place.

Heather Farrington, curator of zoology for the Cincinnati Museum Center, is using DNA from specimens collected more than 100 years ago to help understand the evolution and stresses faced by today’s animals.

Farrington runs the museum’s new state-of-the-art genetics laboratory, which helps researchers study populations of animals over time.

A pair of mathematicians from Australia and France have devised an alternative way to multiply numbers together, while solving an algorithmic puzzle that has perplexed some of the greatest math minds for almost half a century.

For most of us, the way we multiply relatively small numbers is by remembering our times tables – an incredibly handy aid first pioneered by the Babylonians some 4,000 years ago.

Continue reading “Mathematicians Have Discovered an Entirely New Way to Multiply Large Numbers” »

Polymorphism is a remarkable concept in chemistry, materials science, computer science, and biology. Whether it is the ability of a material to exist in two or more crystal structures, a single interface connecting to two different entities, or alternative phenotypes of an organism, polymorphism determines function and properties. In materials science, polymorphism can be found in an impressively wide range of materials, including crystalline materials, minerals, metals, alloys, and polymers. Here we report on polymorphism in a liquid crystal. A bent-core liquid crystal with a single chiral side chain forms two structurally and morphologically significantly different liquid crystal phases solely depending on the cooling rate from the isotropic liquid state. On slow cooling, the thermodynamically more stable oblique columnar phase forms, and on rapid cooling, a not heretofore reported helical microfilament phase. Since structure determines function and properties, the structural color for these phases also differs.

Excitons are quasiparticles made from the excited state of electrons and—according to research being carried out EPFL—have the potential to boost the energy efficiency of our everyday devices.

It’s a whole new way of thinking about electronics. Excitons—or quasiparticles formed when electrons absorb light—stand to revolutionize the building blocks of circuits. Scientists at EPFL have been studying their extraordinary properties in order to design more energy-efficient electronic systems, and have now found a way to better control excitons moving in semiconductors. Their findings appear today in Nature Nanotechnology.

Quasiparticles are temporary phenomena resulting from the interaction between two particles within solid matter. Excitons are created when an electron absorbs a photon and moves into a higher energy state, leaving behind a hole in its previous energy state (called a “valence band” in band theory). The electron and electron hole are bound together through attractive forces, and the two together form what is called an exciton. Once the electron falls back into the hole, it emits a photon and the exciton ceases to exist.

According to an update by MrBeast, Musk is now in the number one spot with the most trees. Second spot goes to MrBeast himself with only 100,002 trees.

Researchers have developed a new printer that produces digital 3D holograms with an unprecedented level of detail and realistic color. The new printer could be used to make high-resolution color recreations of objects or scenes for museum displays, architectural models, fine art or advertisements that do not require glasses or special viewing aids.

“Our 15-year research project aimed to build a hologram printer with all the advantages of previous technologies while eliminating known drawbacks such as expensive lasers, slow printing speed, limited field of view and unsaturated colors,” said research team leader Yves Gentet from Ultimate Holography in France. “We accomplished this by creating the CHIMERA printer, which uses low-cost commercial lasers and high-speed printing to produce holograms with high-quality color that spans a large dynamic range.”

In The Optical Society (OSA) journal Applied Optics, the researchers describe the new printer, which creates holograms with wide fields of view and full parallax on a special photographic material they designed. Full parallax holograms reconstruct an object so that it is viewable in all directions, in this case with a field of view spanning 120 degrees.

Light is the fastest way to distinguish right- and left-handed chiral molecules, which has important applications in chemistry and biology. However, ordinary light only weakly senses molecular handedness. Researchers from the Max Born Institute for Nonlinear Optics and Short Pulse Spectroscopy (MBI), the Israel Institute of Technology (Technion) and Technische Universitaet Berlin (TU Berlin) now report a method to generate and characterize synthetic chiral light, which identifies molecules’ handedness exceptionally distinctly. The results of their joint work have just appeared in Nature Photonics.

Like left and right hands, some molecules in nature have mirror twins. However, while these twin molecules may look similar, some of their properties can be very different. For instance, the handedness—or chirality—of molecules plays an essential role in chemistry, biology, and drug development. While one type of a molecule can cure a disease, its mirror twin—or enantiomer—may be toxic or even lethal.

It is extremely hard to tell opposite chiral molecules apart because they look identical and behave identically unless they interact with another chiral object. Light has long been used to detect chirality—oscillations of the electromagnetic field draw a chiral helix in space along the light propagation direction. Depending on whether the helix twirls clockwise or counterclockwise, the light wave is either right- or left-handed. However, the helix pitch, set by the light wavelength, is about 1000 times bigger than the size of a molecule. So the light helix is a gigantic circle compared to the tiny molecules, which hardly react to its chirality.

RUDN University mathematicians have proven the Hardy-Littlewood-Sobolev (HLS) inequalities for the class of generalized Riesz potentials. These results extend the scope of these potentials in mathematics and physics because the main tools for working with such potentials are based on HLS inequalities. New mathematical tools can greatly simplify calculations in quantum mechanics and other fields of physics. The results of the study are published in the journal Mathematical Notes.

Modern physics describes the world in terms of fields and their potentials—that is, the values of the field at each point. But the physical quantities that we can measure are forces and accelerations, that is, derivatives of the second-order of the potential of the corresponding field. The problem of reconstructing the field configuration with the available values of forces and accelerations observed in experiments is complex and not always analytically solvable. Differentiation operations in multidimensional space—operators are usually used to describe the correlation between the potential of the field and the forces. In particular, electromagnetic and gravitational interactions are described in the language of operators.

Since the potential of the field can be determined up to a constant value, for the convenience of calculations, the initial value of the potential is taken at some point in multidimensional space, or on the border of any spatial area. But in some cases, mathematical models of such fields lead to a singularity, that is, at some points the value of the field becomes infinite, and therefore loses its physical meaning.