Lifeboat Foundation

Molecular programs can rescue cells already engaged in the process of apoptosis or other forms of programmed cell death.

Transplanting embryonic progenitor interneurons into the hippocampus of mouse models of TBI, researchers noticed the neurons migrated to the injury site and made new connections. Following treatment, memory improved and seizures were reduced.

If you want to be as healthy as possible, there are no treadmills or weight machines required.

Don’t just take my word for it — look to the longest-lived people in the world for proof.

People in the world’s Blue Zones— the places around the world with the highest life expectancy — don’t pump iron, run marathons or join gyms.

Immunoglobulin anyone??? r.p.berry & AEWR.

Increased demand — along with the time it takes to manufacture the lifesaving immune globulin medicine — has led to limited supplies.

SOME Geneticists scare the hell out of me??? AEWR.

Will we one day combine tardigrade DNA with our cells to go to Mars?

Chris Mason, a geneticist and associate professor of physiology and biophysics at Weill Cornell University in New York, has investigated the genetic effects of spaceflight and how humans might overcome these challenges to expand our species farther into the solar system. One of the (strangest) ways that we might protect future astronauts on missions to places like Mars, Mason said, might involve the DNA of tardigrades, tiny micro-animals that can survive the most extreme conditions, even the vacuum of space!

Hypoxia, stress induce genetic, physiological adaptations through HIF signaling pathways. Adaptations result in context dependent improvement or disease.

In 2006, Shinya Yamanaka, MD, PhD, made a discovery that revolutionized biomedical research and earned him a Nobel Prize. His lab found that stem cells, the body’s ‘building blocks,’ can be made from just a small sample of skin. These cells, called induced pluripotent stem cells (iPSCs), have changed the way we research disease, bringing us closer than ever to cures — Dr. Yamanaka’s (and NYSCF’s) ultimate goal.

“I am doing whatever it takes to bring this technology to patients,” remarked Dr. Yamanaka, in his keynote address at the 2019 NYSCF Conference. “When I was training as a young surgeon, my father passed away. I couldn’t do anything to help him, and that had a huge impact on me. I truly believe that it is science that will help patients suffering from intractable diseases.”

During the 2019 NYSCF Conference held at The Rockefeller University on October 22–23, over 500 researchers, students, and thought leaders shared their latest findings in translational stem cell research, highlighting how stem cells are being used to illuminate disease mechanisms, discover new therapies, and advance precision medicine.

We all have the potential to pioneer this universe of wonders and discoveries, but we are like genies trapped in bottles. Not only that, the bottle is rusting away, and we have barely gotten to exercise our powers. Yet here we sit, instead of working on the situation, we do what we can to deny death and pretend it’s not happening. We fight tooth and nail for land, gold, traditions, landmarks, and policies, but when it comes to human life, the most valuable of all, something causes us to pull back and let it slide. If gold or a landmark had a genie in it then would it be less valuable?

The author of The Denial of Death, Ernest Becker, writes, “This is the paradox: he is out of nature and hopelessly in it; he is dual, up in the stars and yet housed in a heart-pumping, breath-gasping body that once belonged to a fish and still carries the gill-marks to prove it.” “Man is literally split in two: he has an awareness of his own splendid uniqueness in that he sticks out of nature with a towering majesty, and yet he goes back into the ground a few feet in order blindly and dumbly to rot and disappear forever.” What do you do in a position like that? What are the most sensible courses of action to take for apes wandering along, suddenly finding themselves alight with the vast powers of reflective cognition? Becker says we go mad driving ourselves blind with social and psychological games, that when faced with fight or flight, we flee into rationalizations and distractions.

Being “inauthentic” and “one dimensional”, people are “unable to transcend their social conditioning: the corporation men in the West, the bureaucrats in the East, the tribal men locked up in tradition—man everywhere who doesn’t understand what it means to think for himself and who, if he did, would shrink back at the idea of such audacity and exposure.” Having not completely figured out what it means to think independently yet, humanity as a whole just kind of sinks back into default positions of mimicry and whatever generates tribal acceptance and basic survival needs. When fighting the duality is considered, even the thought of getting a basic grip on it is overwhelming.

Scientists have discovered yet another life-giving treatment for disease using adult stem cells, while the number of substantial medical breakthroughs from life-taking embryonic stem cell research remains essentially zero.

Neuromyelitis optica (NMO), also known as Devic’s disease, causes the immune system to react against the body’s own cells in the central nervous system, particularly the eyes and spinal cord. Those who contract the disease usually lose their eyesight and ability to walk within five years.

Continue reading “Another adult stem cell breakthrough” »