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Jan 10, 2021
Noncognitive Skills, Distinct From Cognitive Abilities, Are Important to Success Across the Life
Posted by Genevieve Klien in categories: education, genetics, neuroscience
Summary: The genetics of neurocognitive skills were associated with higher tolerance of risk, delayed fertility, less healthy-risk behavior, and a greater willingness to forgo immediate gratification.
Source: Columbia University.
Noncognitive skills and cognitive abilities are both important contributors to educational attainment — the number of years of formal schooling that a person completes — and lead to success across the life course, according to a new study from an international team led by researchers at Columbia University Mailman School of Public Health, the University of Texas at Austin, and Vrije Universiteit Amsterdam.
Jan 10, 2021
There’s no way to Measure the Speed of Light in a Single Direction
Posted by Genevieve Klien in categories: cosmology, materials
A new study shows that not even cosmology can verify Einstein’s assumption about the speed of light.
Special relativity is one of the most strongly validated theories humanity has ever devised. It is central to everything from space travel and GPS to our electrical power grid. Central to relativity is the fact that the speed of light in a vacuum is an absolute constant. The problem is, that fact has never been proven.
When Einstein proposed the theory of relativity, it was to explain why light always had the same speed. In the late 1800s it was thought that since light travels as a wave it must be carried by some kind of invisible material known as the luminiferous aether. The reasoning was that waves require a medium, such as sound in air or water waves in water. But if the aether exists, then the observed speed of light must change as the Earth moves through the aether. But measurements to observe aether drift came up null. The speed of light appeared to be constant.
Continue reading “There’s no way to Measure the Speed of Light in a Single Direction” »
Jan 10, 2021
Quantum Entanglement of Electrons Using Heat
Posted by Quinn Sena in categories: computing, quantum physics
Quantum entanglement is key for next-generation computing and communications technology, Aalto researchers can now produce it using temperature differences.
A joint group of scientists from Finland, Russia, China, and the USA have demonstrated that temperature difference can be used to entangle pairs of electrons in superconducting structures. The experimental discovery, published in Nature Communications, promises powerful applications in quantum devices, bringing us one step closer towards applications of the second quantum revolution.
The team, led by Professor Pertti Hakonen from Aalto University, has shown that the thermoelectric effect provides a new method for producing entangled electrons in a new device. “Quantum entanglement is the cornerstone of the novel quantum technologies. This concept, however, has puzzled many physicists over the years, including Albert Einstein who worried a lot about the spooky interaction at a distance that it causes,” says Prof. Hakonen.
Jan 10, 2021
Octopuses, Some Squid Edit RNA Sequences to Adapt to Environment
Posted by Jose Ruben Rodriguez Fuentes in categories: biotech/medical, evolution, genetics
Octopus and squid make strange evolutionary shortcuts in adaptation. Evolution is an intricate process of change.
According to Science Alert, species of squid and octopus may yet have some surprises in store for us. “In a surprising twist, scientists discovered that octopuses, along with some squid and cuttlefish species, routinely edit their RNA (ribonucleic acid) sequences to adapt to their environment,” the article said.
Continue reading “Octopuses, Some Squid Edit RNA Sequences to Adapt to Environment” »
Jan 10, 2021
Distinct hypothalamic control of same- and opposite-sex mounting behaviour in mice
Posted by Saúl Morales Rodriguéz in categories: neuroscience, sex
Ultrasonic vocalizations of male mice distinguish aggressive, male-directed mounting from reproductive, female-directed mounting behaviours, which are represented by distinct ESR1-expressing populations of neurons in the ventromedial hypothalamus and medial preoptic area, respectively.
Jan 10, 2021
Quantifying aphantasia through drawing: Those without visual imagery show deficits in object but not spatial memory
Posted by Saúl Morales Rodriguéz in category: futurism
Congenital aphantasia is a recently characterized variation of experience defined by the inability to form voluntary visual imagery, in individuals who are otherwise high performing. Because of this specific deficit to visual imagery, individuals with aphantasia serve as an ideal group for probing the nature of representations in visual memory, particularly the interplay of object, spatial, and symbolic information. Here, we conducted a large-scale online study of aphantasia and revealed a dissociation in object and spatial content in their memory representations. Sixty-one individuals with aphantasia and matched controls with typical imagery studied real-world scene images, and were asked to draw them from memory, and then later copy them during a matched perceptual condition. Drawings were objectively quantified by 2795 online scorers for object and spatial details. Aphantasic participants recalled significantly fewer objects than controls, with less color in their drawings, and an increased reliance on verbal scaffolding. However, aphantasic participants showed high spatial accuracy equivalent to controls, and made significantly fewer memory errors. These differences between groups only manifested during recall, with no differences between groups during the matched perceptual condition. This object-specific memory impairment in individuals with aphantasia provides evidence for separate systems in memory that support object versus spatial information. The study also provides an important experimental validation for the existence of aphantasia as a variation in human imagery experience.
Jan 10, 2021
Engineered SAM Synthetases for Enzymatic Generation of AdoMet Analogs with Photocaging Groups and Reversible DNA Modification in Cascade Reactions
Posted by Saúl Morales Rodriguéz in categories: biotech/medical, engineering
Methylation and demethylation of DNA, RNA and proteins has emerged as a major regulatory mechanism. Studying the function of these modifications would benefit from tools for their site‐specific inhibition and timed removal. S ‐Adenosyl‐L‐methionine (AdoMet) analogs in combination with methyltransferases (MTases) have proven useful to map or block and release MTase target sites, however their enzymatic generation has been limited to aliphatic groups at the sulfur atom. We engineered a SAM synthetase from Cryptosporidium hominis (PC‐ChMAT) for efficient generation of AdoMet analogs with photocaging groups that are not accepted by any WT MAT reported to date. The crystal structure of PC‐ChMAT at 1.87 Å revealed how the photocaged AdoMet analog is accommodated and guided engineering of a thermostable MAT from Methanocaldococcus jannaschii. PC‐MATs were compatible with DNA‐ and RNA‐MTases, enabling sequence‐specific modification (“writing”) of plasmid DNA and light‐triggered removal (“erasing”).
Jan 10, 2021
Vocal convergence in a multi-level primate society: insights into the evolution of vocal learning
Posted by Saúl Morales Rodriguéz in categories: evolution, genetics, neuroscience
The extent to which nonhuman primate vocalizations are amenable to modification through experience is relevant for understanding the substrate from which human speech evolved. We examined the vocal behaviour of Guinea baboons, Papio papio, ranging in the Niokolo Koba National Park in Senegal. Guinea baboons live in a multi-level society, with units nested within parties nested within gangs. We investigated whether the acoustic structure of grunts of 27 male baboons of two gangs varied with party/gang membership and genetic relatedness. Males in this species are philopatric, resulting in increased male relatedness within gangs and parties. Grunts of males that were members of the same social levels were more similar than those of males in different social levels (N = 351 dyads for comparison within and between gangs, and N = 169 dyads within and between parties), but the effect sizes were small. Yet, acoustic similarity did not correlate with genetic relatedness, suggesting that higher amounts of social interactions rather than genetic relatedness promote the observed vocal convergence. We consider this convergence a result of sensory–motor integration and suggest this to be an implicit form of vocal learning shared with humans, in contrast to the goal-directed and intentional explicit form of vocal learning unique to human speech acquisition.
One of the key preconditions for the development of speech is the ability to adjust vocal output in response to auditory input. Humans are exceptionally proficient at vocal learning. Although effortless speech learning is confined to the early years [1], humans still possess the ability to imitate sounds voluntarily and acquire further languages throughout their lives. Numerous comparative studies have aimed at elucidating the evolutionary origins of vocal learning within the primate lineage, to uncover the extent to which nonhuman primates reveal evidence for vocal plasticity, and whether such plasticity may be conceived as a pre-adaptation for the evolution of speech [2, 3].
Despite considerable research effort, it appears that the ability to learn sounds from auditory experience in most nonhuman primate species is limited. Unlike humans or some songbird species, nonhuman primates are not obligatory vocal learners that require species-specific auditory input to develop their normal vocal repertoires [4, 5]. Early attempts to train a young chimpanzee to produce speech sounds yielded disappointing results and prompted most of the ‘ape language’ projects to turn to another modality, using either symbol systems or sign languages [6]. Studies of the neural basis of vocal production in different monkey species found that the animals lack the neural connections necessary for the volitional control over the fine structure of vocalizations, although they exert greater control over the usage of calls (reviewed in [2]).
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