Lifeboat Foundation

Circa 2016

Air pollution has a significant and pervasive impact on public health. According to the World Health Organization, it is now considered “the world’s largest single environmental health risk,” with more than three million people dying every year as a result. This is more than twice the number of people that die in vehicle accidents each year.

Health and safety are important to us. Just as we’ve designed Model S and Model X to avoid collisions or protect their occupants when one happens, we felt compelled to protect them against the statistically more relevant hazard of air pollution*. Inspired by the air filtration systems used in hospitals, clean rooms, and the space industry, we developed a HEPA filtration system capable of stripping the outside air of pollen, bacteria, and pollution before they enter the cabin and systematically scrubbing the air inside the cabin to eliminate any trace of these particles. The end result is a filtration system hundreds of times more efficient than standard automotive filters, capable of providing the driver and her passengers with the best possible cabin air quality no matter what is happening in the environment around them.

Continue reading “Putting the Tesla HEPA Filter and Bioweapon Defense Mode to the Test” »

Circa 2000

The intentional release of biological agents by belligerents or terrorists is a possibility that has recently attracted increased attention. Law enforcement agencies, military planners, public health officials, and clinicians are gaining an increasing awareness of this potential threat. From a military perspective, an important component of the protective pre-exposure armamentarium against this threat is immunization. In addition, certain vaccines are an accepted component of postexposure prophylaxis against potential bioterrorist threat agents. These vaccines might, therefore, be used to respond to a terrorist attack against civilians. We review the development of vaccines against 10 of the most credible biological threats.

Most simply, the phrase “genome editing” represents tools and techniques that biotechnologists use to edit the genome — that is, the DNA or RNA of plants, animals, and bacteria. Though the earliest versions of genome editing technology have existed for decades, the introduction of CRISPR in 2013 “brought major improvements to the speed, cost, accuracy, and efficiency of genome editing.”

CRISPR, or Clustered Regularly Interspersed Short Palindromic Repeats, is actually an ancient mechanism used by bacteria to remove viruses from their DNA. In the lab, researchers have discovered they can replicate this process by creating a synthetic RNA strand that matches a target DNA sequence in an organism’s genome. The RNA strand, known as a “guide RNA,” is attached to an enzyme that can cut DNA. After the guide RNA locates the targeted DNA sequence, the enzyme cuts the genome at this location. DNA can then be removed, and new DNA can be added. CRISPR has quickly become a powerful tool for editing genomes, with research taking place in a broad range of plants and animals, including humans.

A significant percentage of genome editing research focuses on eliminating genetic diseases. However, with tools like CRISPR, it also becomes possible to alter a pathogen’s DNA to make it more virulent and more contagious. Other potential uses include the creation of “‘killer mosquitos,’ plagues that wipe out staple crops, or even a virus that snips at people’s DNA.”

The potential threat of biological warfare with a specific agent is proportional to the susceptibility of the population to that agent. Preventing disease after exposure to a biological agent is partially a function of the immunity of the exposed individual. The only available countermeasure that can provide immediate immunity against a biological agent is passive antibody. Unlike vaccines, which require time to induce protective immunity and depend on the host’s ability to mount an immune response, passive antibody can theoretically confer protection regardless of the immune status of the host. Passive antibody therapy has substantial advantages over antimicrobial agents and other measures for postexposure prophylaxis, including low toxicity and high specific activity. Specific antibodies are active against the major agents of bioterrorism, including anthrax, smallpox, botulinum toxin, tularemia, and plague. This article proposes a biological defense initiative based on developing, producing, and stockpiling specific antibody reagents that can be used to protect the population against biological warfare threats.

Defense strategies against biological weapons include such measures as enhanced epidemiologic surveillance, vaccination, and use of antimicrobial agents, with the important caveat that the final line of defense is the immune system of the exposed individual. The potential threat of biological warfare and bioterrorism is inversely proportional to the number of immune persons in the targeted population. Thus, biological agents are potential weapons only against populations with a substantial proportion of susceptible persons. For example, smallpox virus would not be considered a useful biological weapon against a population universally immunized with vaccinia.

Vaccination can reduce the susceptibility of a population against specific threats provided that a safe vaccine exists that can induce a protective response. Unfortunately, inducing a protective response by vaccination may take longer than the time between exposure and onset of disease. Moreover, many vaccines require multiple doses to achieve a protective immune response, which would limit their usefulness in an emergency vaccination program to provide rapid prophylaxis after an attack. In fact, not all vaccine recipients mount a protective response, even after receiving the recommended immunization schedule. Persons with impaired immunity are often unable to generate effective response to vaccination, and certain vaccines may be contraindicated for them.

Satellites are studying the impacts on pollution and night lighting of measures taken to slow the spread of COVID-19.

Circa 2019

The development of new so-called metamaterials could lead to dramatic advances in military technology, particularly the ability to hide from sensors—even the human eye. Metamaterials, engineered composites designed to manipulate the electromagnetic spectrum, could lead to “invisible” tanks and armored vehicles, submarines undetectable by sonar, and weapons with improved seekers and guidance systems.

The big caveat though is that metamaterials are currently pretty difficult to manufacture and are still years away from full-scale production.

Continue reading “How Metamaterials Could Lead to Invisible Tanks and Super-Stealthy Submarines” »

Scientists have discovered some of the largest bacteria-infecting virus out there.

The most common materials in the world, including plastic, steel, glass or wood have distinct molecular and chemical properties that give them intrinsic qualities, such as strength, flexibility or transparency. But an entirely different class of materials, called metamaterials, are coming onto the scene.

Artificially engineered, these materials have unique geometries and physical structures that can manipulate any mechanical or electromagnetic wave that passes through them. Metamaterials can perform a host of futuristic tricks; they can absorb sound waves to produce silence, bend light to create an invisibility cloak and dampen seismic waves to safeguard a building against an earthquake.

Metamaterial applications are numerous, but here are five of the coolest.

COVID-19 may be just the beginning of mass pandemics.