Lifeboat Foundation

An interesting new paper about alien civilizations on our level of technology which may be able to observe us. For more info, see:

Our planet’s shadow against the Sun could have been seen from thousands of nearby solar systems.

In 2020, DeepMind solved one of biology’s biggest challenges. Now it’s working on using its AI to find drugs to target neglected diseases.

Putting IT security practices in place will enable organizations to prevent ransomware attacks and help IT teams combat security challenges.

According to Check Point research, the number of organizations affected by ransomware has been growing at 9% monthly since the start of the year. From WannaCry, Petya, and SamSam to Ryuk, these ransomware attacks have caused huge financial and reputation losses for both public and private sector organizations – the recent attacks on Colonial Pipeline are just the latest example.

Organizations are in a tight spot to prevent these cyberattacks and safeguard what they have built over the years. While IT teams are already battling the challenges of securing remote endpoints in the changing work sphere, the rise in cyberattacks has added additional responsibilities on their shoulders.

About 2.2 billion people globally lack reliable access to clean drinking water, according to the United Nations, and the growing impacts of climate change are likely to worsen this reality.

Solar steam generation (SSG) has emerged as a promising renewable energy technology for water harvesting, desalination, and purification that could benefit people who need it most in remote communities, disaster-relief areas, and developing nations. In Applied Physics Letters, Virginia Tech researchers developed a synthetic tree to enhance SSG.

SSG turns solar energy into heat. Water from a storage tank continuously wicks up small, floating porous columns. Once water reaches the layer of photothermal material, it evaporates, and the steam is condensed into drinking water.

Filaments of dark matter and galaxies, which can stretch millions of light-years, might help astronomers figure out the origins of cosmic spin.

Boeing finished loading hydrazine and nitrogen tetroxide maneuvering propellants over the weekend into the company’s second space-rated Starliner capsule at the Kennedy Space Center, days after stacking of its Atlas 5 launcher began a few miles away at Cape Canaveral Space Force Station.

The capsule is scheduled to launch July 30 at 2:53 p.m. EDT (1853 GMT) on a test flight to the space station. If all goes according to plan, it will clear the way for Boeing to carry astronauts to the station, possibly before the end of this year.

That will be welcome news to NASA, which has funded the Starliner spacecraft’s development through its a commercial crew program in a cost-sharing arrangement with Boeing. NASA’s commercial crew contracts with Boeing since 2010 are valued at more than $5 billion.

If you walk down the street shouting out the names of every object you see — garbage truck! bicyclist! sycamore tree! — most people would not conclude you are smart. But if you go through an obstacle course, and you show them how to navigate a series of challenges to get to the end unscathed, they would.

Most machine learning algorithms are shouting names in the street. They perform perceptive tasks that a person can do in under a second. But another kind of AI — deep reinforcement learning — is strategic. It learns how to take a series of actions in order to reach a goal. That’s powerful and smart — and it’s going to change a lot of industries.

Two industries on the cusp of AI transformations are manufacturing and supply chain. The ways we make and ship stuff are heavily dependent on groups of machines working together, and the efficiency and resiliency of those machines are the foundation of our economy and society. Without them, we can’t buy the basics we need to live and work.

The Environmental Protection Agency (EPA) will reconsider decisions underlying a rule governing emissions of a chemical that it has deemed carcinogenic following a request from an industry group.

The agency told stakeholders in letters dated last week that it would reconsider its risk information for ethylene oxide, a chemical the EPA currently says is carcinogenic if it is inhaled.

The EPA also said it would reconsider its prior decision not to use a much lower risk finding from the state of Texas as an alternative risk value.

The scientists found “biotin paint” on a protein named RSK1, which is part of a complex that keeps a nearby group of proteins, called RAS proteins, dormant. The scientists were surprised to discover that when they inactivated mutant KRAS, the nearby RSK1 complex stopped working as well. This allowed the RAS proteins to activate and take over the work of the missing mutant KRAS.

Cancer cells can become resistant to treatments through adaptation, making them notoriously tricky to defeat and highly lethal. Cold Spring Harbor Laboratory (CSHL) Cancer Center Director David Tuveson and his team investigated the basis of “adaptive resistance” common to pancreatic cancer. They discovered one of the backups to which these cells switch when confronted with cancer-killing drugs.

KRAS is a gene that drives cell division. Most pancreatic cancers have a mutation in the KRAS protein, causing uncontrolled growth. But, drugs that shut off mutant KRAS do not stop the proliferation. The cancer cells find a way to bypass the blockage and keep on dividing. Derek Cheng, the lead author of the study and a former Medical Scientist Training Program student in the Tuveson lab, compares this process to backup engines on a ship. He says, “You take away your main engine, you’re kind of on some backup engines. But it’s getting by on those. The ship isn’t sinking yet. It’s still moving at a slower pace. Ultimately what we want to do is sink the ship.”

Continue reading “How pancreatic cancer cells dodge drug treatments” »