American company Pfizer cemented a deal with China to sell its antiviral medication Paxlovid. This is an addition to the supply of Covid treatments in the country. Watch further to know more.
According to a recent paper by a math professor at the University of Arkansas, the existence of life on Earth provides proof that abiogenesis is relatively easy on planets similar to Earth, refuting the “Carter argument” conclusion.
Does the presence of life on Earth provide any insight into the likelihood that abiogenesis—the process by which life first emerges from inorganic substances—occurs elsewhere? That is a question that has baffled scientists for a while, as well as everyone else inclined to think about it.
Companies are working to avoid a “quantum winter” that could stall progress and freeze startup investments.
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An alloy made of almost equal amounts of chromium, cobalt and nickel resists fracturing even at incredibly cold temperatures, which could make it useful for building spacecraft.
High on Life co-creator Justin Roiland explained AI art makes the game feel like a ‘strange alternate dimension’.
Since as far back as Ancient Greece, humans have been fascinated by the solar system. However, Japanese researchers have now collected asteroid data that provides insights into the development of the solar system that earlier scientists such as Ptolemy, Galileo, and Copernicus could only have dreamed of.
Asteroid explorer Hayabusa2, launched in 2014, set out for Ryugu, a carbon-rich C-type asteroid. In 2018, it arrived in the area of Ryugu, conducting a number of remote observations and collecting samples from two locations on the asteroid. Before the launch of Hayabusa2, a research team at Osaka University had been developing a non-destructive method of light element analysis utilizing muons to analyze Ryugu.
So we designed CAR-T cells to produce IL-2 using synNotch. Now, when a CAR-T cell encounters a tumor, it produces IL-2 within the tumor instead of outside it, avoiding causing harm to surrounding healthy cells. Because synNotch is able to bypass the barriers tumors put up, it is able to help T cells amp up and maintain the amount of IL-2 they can make, allowing the T cells to keep functioning even in a hostile microenvironment.
We tested our CAR-T cells modified with synNotch on mice with pancreatic cancer and melanoma. We found that CAR-T cells with synNotch-induced IL-2 were able to produce enough extra IL-2 to overcome the tumors’ defensive barriers and fully activate, completely eliminating the tumors. While all of the mice receiving synNotch modified CAR-T cells survived, none of the CAR-T-only mice did.
