Chimeric antigen receptor T-cell (CAR-T) therapy, already approved for certain blood cancers, is generating excitement in early tests against autoimmune diseases. Designed to wipe out a whole class of immune cells, the treatment holds promise but comes with potentially serious risks.
The hypertension drug rilmenidine has been shown to slow down aging in worms, an effect that in humans could hypothetically help us live longer and keep us healthier in our latter years.
Previous research has shown rilmenidine mimics the effects of caloric restriction on a cellular level. Reducing available energy while maintaining nutrition within the body has been shown to extend lifespans in several animal models.
Whether this translates to human biology, or is a potential risk to our health, is a topic of ongoing debate. Finding ways to achieve the same benefits without the costs of extreme calorie cutting could lead to new ways to improve health in old age.
Cheng-Yen Yang, Hsiang-Wei Huang, Wenhao Chai, Zhongyu Jiang, Jenq-Neng Hwang University of Washington 2024 https://arxiv.org/abs/2411.
A tool that can…
Official repository of Adapting Segment Anything Model for Zero-Shot Visual Tracking with Motion-Aware Memory’ — yangchris11/samurai.
Scientists now use a new mathematical model to reveal the geometry of photons, previously elusive.
A groundbreaking study from the University of Birmingham has revealed the shape of a photon and its interaction with quantum emitters.
As physicists continue their struggle to find and explain the origin of dark matter, the approximately 80% of the matter in the universe that we can’t see and so far haven’t been able to detect, researchers have now proposed a model where it is produced before the Big Bang.
Their idea is that dark matter would be produced during a infinitesimally short inflationary phase when the size of the universe quickly expanded exponentially. The new model was published in Physical Review Letters by three scientists from Texas in the US.
An intriguing idea among cosmologists is that dark matter was produced through its interaction with a thermal bath of some species, and its abundance is created by “freeze-out” or “freeze-in.” In the freeze-out scenario, dark matter is in chemical equilibrium with the bath at the earliest times—the concentration of each does not change with time.
Memory, a fundamental aspect of human cognition and consciousness, is multifaceted and extends beyond traditional conceptualizations of mental recall. This review article explores memory through various lenses, including brain-based, body-based, and cellular mechanisms. At its core, memory involves the encoding, storage, and retrieval of information. Advances in neuroscience reveal that synaptic changes and molecular modifications, particularly in the hippocampus, are crucial for memory consolidation. Additionally, body memory, or somatic memory, highlights how sensory experiences and traumatic events are stored and influence behavior, underscoring the role of implicit memory. Multiple studies have demonstrated that memories can be encoded and stored in cells. Evidence suggests that these memories can then be transferred between individuals through organ transplantation.
The ability to control and optimize electron behavior is crucial for realizing the potential of the best quantum materials.
Scientists at Loughborough University have made an exciting breakthrough in understanding how fine-tuning the behavior of electrons in quantum materials can unlock the next generation of advanced technologies.
Was dark matter created some time after the Big Bang? Gravitational wave detectors could soon find the answer.
For now, the duo’s results suggest that the Dark Big Bang is far less constrained by past observations than Freese and Winkler originally anticipated. As Ilie explains, their constraints could soon be put to the test.
“We examined two Dark Big Bang scenarios in this newly found parameter space that produce gravitational wave signals in the sensitivity ranges of existing and upcoming surveys,” he says. “In combination with those considered in Freese and Winkler’s paper, these cases could form a benchmark for gravitational wave researchers as they search for evidence of a Dark Big Bang in the early universe.”
Continue reading “Delayed Big Bang for dark matter could be detected in gravitational waves” »
The U.S. “is in possession of UAP technologies, as are some of our adversaries,” he said during a recent Congressional hearing.
